ITGA2 Antibody, HRP conjugated

Datasheet
Code CSB-PA011864LB01HU
Size US$299
Uniprot No. P17301
Protocols ELISA Protocol
Immunogen Recombinant Human Integrin alpha-2 protein (188-365AA)
Raised in Rabbit
Species Reactivity Human
Tested Applications ELISA
Relevance Integrin alpha-2/beta-1 is a receptor for laminin, collagen, collagen C-propeptides, fibronectin and E-cadherin. It recognizes the proline-hydroxylated sequence G-F-P-G-E-R in collagen. It is responsible for adhesion of platelets and other cells to collagens, modulation of collagen and collagenase gene expression, force generation and organization of newly synthesized extracellular matrix.
Form Liquid
Conjugate HRP
Storage Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Purification Method >95%, Protein G purified
Isotype IgG
Clonality Polyclonal
Alias Integrin alpha-2 (CD49 antigen-like family member B) (Collagen receptor) (Platelet membrane glycoprotein Ia) (GPIa) (VLA-2 subunit alpha) (CD antigen CD49b), ITGA2, CD49B
Immunogen Species Homo sapiens (Human)
Research Area Signal Transduction
Target Names ITGA2
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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Function Integrin alpha-2/beta-1 is a receptor for laminin, collagen, collagen C-propeptides, fibronectin and E-cadherin. It recognizes the proline-hydroxylated sequence G-F-P-G-E-R in collagen. It is responsible for adhesion of platelets and other cells to collagens, modulation of collagen and collagenase gene expression, force generation and organization of newly synthesized extracellular matrix.; FUNCTION
Subcellular Location Membrane, Single-pass type I membrane protein
Protein Families Integrin alpha chain family
Database Links

HGNC: 6137

OMIM: 192974

KEGG: hsa:3673

STRING: 9606.ENSP00000296585

UniGene: Hs.482077

Pathway PI3K-Akt signaling pathway
Focal adhesion
Regulation of actin cytoskeleton
Hematopoietic cell lineage

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