Mapt Antibody, HRP conjugated

^Datasheet

Code	CSB-PA013481YB01RA
Size	US$299
Uniprot No.	P19332
Immunogen	Recombinant Rat Microtubule-associated protein tau protein (2-752AA)
Raised in	Rabbit
Species Reactivity	Rat
Tested Applications	ELISA
Relevance	Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by tau localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization.
Form	Liquid
Conjugate	HRP
Storage Buffer	Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Purification Method	>95%, Protein G purified
Isotype	IgG
Clonality	Polyclonal
Alias	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau), Mapt, Mtapt Tau
Immunogen Species	Rattus norvegicus (Rat)
Protocols	ELISA Protocol
Research Area	Neuroscience
Target Names	Mapt
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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Function	Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by tau localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization.
Subcellular Location	Cytoplasm, cytosol, Cell membrane, Peripheral membrane protein, Cytoplasmic side, Cytoplasm, cytoskeleton, Cell projection, axon
Tissue Specificity	Expressed in neurons. The larger forms (isoform tau-A and isoform tau-B) are preferentially expressed in the peripheral nervous system while the other are expressed in the central nervous system. Low amounts of the larger forms are also found in limited a
Database Links	STRING: 10116.ENSRNOP00000006856 UniGene: Rn.2455
Pathway	MAPK signaling pathway

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Mapt Antibodies for Rattus norvegicus (Rat)

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CSB-PA013481YC01RA	Mapt Antibody, FITC conjugated	Rat	ELISA
CSB-PA013481YA01RA	Mapt Antibody	Rat	ELISA
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Mapt Proteins for Rattus norvegicus (Rat)

Code	Product Name	Source
CSB-EP013481RA	Recombinant rat Microtubule-associated protein tau	E.coli
CSB-YP013481RA	Recombinant Rat Microtubule-associated protein tau(Mapt)	Yeast
CSB-BP013481RA CSB-MP013481RA	Recombinant Rat Microtubule-associated protein tau(Mapt)	Baculovirus Mammalian cell

Mapt ELISA Kit for Rattus norvegicus (Rat)

Code	Product Name	Sample Types	Sensitivity
CSB-E13729r	Rat Tau Proteins ELISA kit	serum, plasma, cerebrospinal fluid (CSF)	15.6 pg/mL

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