NUBP2 Antibody, HRP conjugated

Datasheet
Code CSB-PA896918LB01HU
Size US$299
Uniprot No. Q9Y5Y2
Immunogen Recombinant Human Cytosolic Fe-S cluster assembly factor NUBP2 protein (54-170AA)
Raised in Rabbit
Species Reactivity Human
Tested Applications ELISA
Relevance Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins. Negatively regulates cilium formation and structure.
Form Liquid
Conjugate HRP
Storage Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Purification Method >95%, Protein G purified
Isotype IgG
Clonality Polyclonal
Alias Cytosolic Fe-S cluster assembly factor NUBP2 (Nucleotide-binding protein 2) (NBP 2), NUBP2
Immunogen Species Homo sapiens (Human)
Protocols ELISA Protocol
Research Area Others
Target Names NUBP2
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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Function Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins. Negatively regulates cilium formation and structure.
Subcellular Location Nucleus, Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, Cytoplasm, Cytoplasm, cytoskeleton, cilium axoneme, Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole, Cytoplasm, cytoskeleton, microtubule organizing center
Protein Families Mrp/NBP35 ATP-binding proteins family, NUBP2/CFD1 subfamily
Tissue Specificity Widely expressed with highest expression in skeletal muscle.
Database Links

HGNC: 8042

OMIM: 610779

KEGG: hsa:10101

STRING: 9606.ENSP00000262302

UniGene: Hs.256549

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