PARG Antibody, HRP conjugated

Code CSB-PA773045LB01HU
Size US$299
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Product Details

Full Product Name Rabbit anti-Homo sapiens (Human) PARG Polyclonal antibody
Uniprot No. Q86W56
Target Names PARG
Alternative Names ADP riboseglycohydrolase antibody; Mitochondrial poly(ADP ribose) glycohydrolase antibody; Parg antibody; PARG_HUMAN antibody; PARG99 antibody; Poly antibody; poly (ADP ribose) glycohydrolase antibody; poly(ADP-ribose) glycohydrolase 60 kDa isoform antibody; Poly(ADP-ribose) glycohydrolase antibody
Raised in Rabbit
Species Reactivity Human
Immunogen Recombinant Human Poly(ADP-ribose) glycohydrolase protein (1-348AA)
Immunogen Species Homo sapiens (Human)
Conjugate HRP
Clonality Polyclonal
Isotype IgG
Purification Method >95%, Protein G purified
Concentration It differs from different batches. Please contact us to confirm it.
Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form Liquid
Tested Applications ELISA
Protocols ELISA Protocol
Troubleshooting and FAQs Antibody FAQs
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

(From Uniprot)
Poly(ADP-ribose) synthesized after DNA damage is only present transiently and is rapidly degraded by poly(ADP-ribose) glycohydrolase
Gene References into Functions
  1. The catalytic efficiency (kcat/Km) of rBPHL for homocysteine thiolactone hydrolysis was 7.7 x 10(4) M(-1)s(-1), orders of magnitude higher than that of PON1 or Blmh, indicating a more significant physiological role for BPHL in detoxifying HCTL PMID: 25333274
  2. BPHL catalyzes the hydrolytic activation of the antiviral prodrugs valacyclovir and valganciclovir. PMID: 15832508
  3. BPHL is a serine hydrolase that catalyzes the hydrolytic activation of amino acid ester prodrugs of nuceloside analogs such as valacyclovir and valganciclovir. PMID: 12732646
Subcellular Location Isoform 1: Nucleus, Note=Colocalizes with PCNA at replication foci, Relocalizes to the cytoplasm in response to DNA damage, SUBCELLULAR LOCATION: Isoform 2: Cytoplasm
Protein Families Poly(ADP-ribose) glycohydrolase family
Tissue Specificity Ubiquitously expressed.
Database Links

HGNC: 8605

OMIM: 603501

KEGG: hsa:8505

STRING: 9606.ENSP00000384408

UniGene: Hs.10136


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