Code | CSB-PA017451KA01HU |
Size | US$398 |
Image |
Uniprot No. | O60260 | ||||||
Target Names | PRKN | ||||||
Alternative Names | PARK2;AR-JP;LPRS2;PDJ;PRKN;Parkin | ||||||
Raised in | Rabbit | ||||||
Species Reactivity | Human,Mouse,Rat | ||||||
Immunogen | Recombinant protein of Human PARK2 | ||||||
Immunogen Species | Homo sapiens (Human) | ||||||
Isotype | IgG | ||||||
Purification Method | Affinity purification | ||||||
Concentration | It differs from different batches. Please contact us to confirm it. | ||||||
Buffer | Store at -20°C or -80°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. | ||||||
Tested Applications | ELISA,WB,IHC | ||||||
Recommended Dilution |
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Protocols | ELISA Protocol Western Blotting(WB) Protocol Immunohistochemistry (IHC) Protocol |
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Troubleshooting and FAQs | Antibody FAQs | ||||||
Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | ||||||
Lead Time | Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time. | ||||||
Still Have Questions? | Leave a Message or Start an on-line Chat |
Function | Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins, such as BCL2, SYT11, CCNE1, GPR37, RHOT1/MIRO1, MFN1, MFN2, STUB1, SNCAIP, SEPT5, TOMM20, USP30, ZNF746 and AIMP2 |
Involvement in disease | Parkinson disease (PARK); Parkinson disease 2 (PARK2) |
Subcellular Location | Cytoplasm, cytosol, Nucleus, Endoplasmic reticulum, Mitochondrion |
Protein Families | RBR family, Parkin subfamily |
Tissue Specificity | Highly expressed in the brain including the substantia nigra. Expressed in heart, testis and skeletal muscle. Expression is down-regulated or absent in tumor biopsies, and absent in the brain of PARK2 patients. Overexpression protects dopamine neurons fro |
Database Links |
HGNC: 8607 OMIM: 168600 KEGG: hsa:5071 STRING: 9606.ENSP00000355865 UniGene: Hs.132954 |
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Tel: 301-363-4651
Email: support@cusabio.com
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