PIGN Antibody, Biotin conjugated

Datasheet
Code CSB-PA017977LD01HU
Size US$299
Uniprot No. O95427
Immunogen Recombinant Human GPI ethanolamine phosphate transferase 1 protein (27-181AA)
Raised in Rabbit
Species Reactivity Human
Tested Applications ELISA
Relevance Ethanolamine phosphate transferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers ethanolamine phosphate to the first alpha-1,4-linked mannose of the glycosylphosphatidylinositol precursor of GPI-anchor (By similarity). May act as suppressor of replication stress and chromosome missegregation.
Form Liquid
Conjugate Biotin
Storage Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Purification Method >95%, Protein G purified
Isotype IgG
Clonality Polyclonal
Alias GPI ethanolamine phosphate transferase 1 (EC 2.-.-.-) (MCD4 homolog) (Phosphatidylinositol-glycan biosynthesis class N protein) (PIG-N), PIGN, MCD4
Immunogen Species Homo sapiens (Human)
Protocols ELISA Protocol
Research Area Tags & Cell Markers
Target Names PIGN
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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Function Ethanolamine phosphate transferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers ethanolamine phosphate to the first alpha-1,4-linked mannose of the glycosylphosphatidylinositol precursor of GPI-anchor (By similarity). May act as suppressor of replication stress and chromosome missegregation.
Involvement in disease Multiple congenital anomalies-hypotonia-seizures syndrome 1 (MCAHS1)
Subcellular Location Endoplasmic reticulum membrane, Multi-pass membrane protein
Protein Families PIGG/PIGN/PIGO family, PIGN subfamily
Database Links

HGNC: 8967

OMIM: 606097

KEGG: hsa:23556

STRING: 9606.ENSP00000350263

UniGene: Hs.157031

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