SLC4A5 Antibody, HRP conjugated

Code CSB-PA874837LB01HU
Size US$299
Uniprot No. Q9BY07
Protocols ELISA Protocol
Immunogen Recombinant Human Electrogenic sodium bicarbonate cotransporter 4 protein (1071-1137AA)
Raised in Rabbit
Species Reactivity Human
Tested Applications ELISA
Relevance Mediates sodium- and bicarbonate-dependent electrogenic sodium bicarbonate cotransport, with a Na(+):HCO3(-) stoichiometry of 2:1. May have a housekeeping function in regulating the pH of tissues in which it is expressed. May play a role in mediating Na(+):HCO3(-) cotransport in hepatocytes and intrahepatic cholangiocytes. Also may be important in protecting the renal paranchyma from alterations in urine pH.
Form Liquid
Conjugate HRP
Storage Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Purification Method >95%, Protein G purified
Isotype IgG
Clonality Polyclonal
Alias Electrogenic sodium bicarbonate cotransporter 4 (NBCe2) (Solute carrier family 4 member 5), SLC4A5, NBC4
Immunogen Species Homo sapiens (Human)
Research Area Neuroscience
Target Names SLC4A5
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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Function Mediates sodium- and bicarbonate-dependent electrogenic sodium bicarbonate cotransport, with a Na(+)
Subcellular Location Apical cell membrane, Multi-pass membrane protein
Protein Families Anion exchanger (TC 2.A.31) family
Tissue Specificity Highest expression observed in liver, spleen and testis; moderate expression in the choroid plexus, hippocampus, cerebrum and cerebellum of brain, and in kidney cortex and kidney medulla. Also observed in heart, pancreas, muscle, lung, placenta, stomach a
Database Links

HGNC: 18168

OMIM: 606757

KEGG: hsa:57835

STRING: 9606.ENSP00000350475

UniGene: Hs.594099

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