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| Code | CSB-PA08467C0Rb |
| Size | US$299 |
| Uniprot No. | Q9Y6Q6 |
| Protocols | ELISA Protocol |
| Immunogen | Recombinant Human Tumor necrosis factor receptor superfamily member 11A protein (28-202AA) |
| Raised in | Rabbit |
| Species Reactivity | Human |
| Tested Applications | ELISA |
| Relevance | Receptor for TNFSF11/RANKL/TRANCE/OPGL; essential for RANKL-mediated osteoclastogenesis. Involved in the regulation of interactions between T-cells and dendritic cells. |
| Form | Liquid |
| Conjugate | FITC |
| Storage Buffer | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method | >95%, Protein G purified |
| Isotype | IgG |
| Clonality | Polyclonal |
| Alias | Tumor necrosis factor receptor superfamily member 11A (Osteoclast differentiation factor receptor) (ODFR) (Receptor activator of NF-KB) (CD antigen CD265), TNFRSF11A, RANK |
| Immunogen Species | Human |
| Research Area | Immunology |
| Target Names | TNFRSF11A |
| Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Still Have Questions? | Leave a Message or Start an on-line Chat |
| Function | Receptor for TNFSF11/RANKL/TRANCE/OPGL; essential for RANKL-mediated osteoclastogenesis. Involved in the regulation of interactions between T-cells and dendritic cells. |
| Involvement in disease | Familial expansile osteolysis (FEO); Paget disease of bone 2, early-onset (PDB2); Osteopetrosis, autosomal recessive 7 (OPTB7) |
| Subcellular Location | Isoform 1: Cell membrane, Single-pass type I membrane protein, SUBCELLULAR LOCATION: Isoform RANK-e5a: Cell membrane, Single-pass type I membrane protein |
| Tissue Specificity | Ubiquitous expression with high levels in skeletal muscle, thymus, liver, colon, small intestine and adrenal gland. |
| Database Links |
HGNC: 11908 OMIM: 174810 KEGG: hsa:8792 STRING: 9606.ENSP00000465500 UniGene: Hs.204044 |
| Pathway |
NF-kappa B signaling pathway
Osteoclast differentiation |
TNFRSF11A Antibodies for Human
| Code | Product Name | Species Reactivity | Application |
|---|---|---|---|
| CSB-PA08467A0Rb | TNFRSF11A Antibody | Human | ELISA, WB, IF |
| CSB-PA08467B0Rb | TNFRSF11A Antibody, HRP conjugated | Human | ELISA |
| CSB-PA08467D0Rb | TNFRSF11A Antibody, Biotin conjugated | Human | ELISA |
TNFRSF11A Antibodies for Homo sapiens (Human)
| Code | Product Name | Species Reactivity | Application |
|---|---|---|---|
| CSB-PA925190 | TNFRSF11A Antibody | Human,Mouse | ELISA,WB |
TNFRSF11A Proteins for Homo sapiens (Human)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP896933HU CSB-EP896933HU CSB-BP896933HU CSB-MP896933HU |
Recombinant Human Tumor necrosis factor receptor superfamily member 11A(TNFRSF11A),partial | Yeast E.coli Baculovirus Mammalian cell |
| CSB-AP002321HU | Recombinant Human Tumor necrosis factor receptor superfamily member 11A protein(TNFRSF11A) (Active) | E.coli |
| CSB-RP084674h | Recombinant Human Tumor necrosis factor receptor superfamily member 11A(TNFRSF11A),partial | E.coli |
TNFRSF11A ELISA Kit for Homo sapiens (Human)
| Code | Product Name | Sample Types | Sensitivity |
|---|---|---|---|
| CSB-E13539h | Human Soluble Receptor Activator of Nuclear Factor-kB,sRANK ELISA Kit | serum, plasma, tissue homogenates, cell lysates | 4.68 pg/mL |
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