TPP1 Antibody, FITC conjugated

Datasheet
Code CSB-PA024113LC01HU
Size US$299
Uniprot No. O14773
Protocols ELISA Protocol
Immunogen Recombinant Human Tripeptidyl-peptidase 1 protein (371-480AA)
Raised in Rabbit
Species Reactivity Human
Tested Applications ELISA
Relevance Lysosomal serine protease with tripeptidyl-peptidase I activity. May act as a non-specific lysosomal peptidase which generates tripeptides from the breakdown products produced by lysosomal proteinases. Requires substrates with an unsubstituted N-terminus (By similarity).
Form Liquid
Conjugate FITC
Storage Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Purification Method >95%, Protein G purified
Isotype IgG
Clonality Polyclonal
Alias Tripeptidyl-peptidase 1 (TPP-1) (EC 3.4.14.9) (Cell growth-inhibiting gene 1 protein) (Lysosomal pepstatin-insensitive protease) (LPIC) (Tripeptidyl aminopeptidase) (Tripeptidyl-peptidase I) (TPP-I), TPP1, CLN2
Immunogen Species Human
Research Area Neuroscience
Target Names TPP1
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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Function Lysosomal serine protease with tripeptidyl-peptidase I activity. May act as a non-specific lysosomal peptidase which generates tripeptides from the breakdown products produced by lysosomal proteinases. Requires substrates with an unsubstituted N-terminus (By similarity).
Involvement in disease Ceroid lipofuscinosis, neuronal, 2 (CLN2); Spinocerebellar ataxia, autosomal recessive, 7 (SCAR7)
Subcellular Location Lysosome, Melanosome
Tissue Specificity Detected in all tissues examined with highest levels in heart and placenta and relatively similar levels in other tissues.
Database Links

HGNC: 2073

OMIM: 204500

KEGG: hsa:1200

STRING: 9606.ENSP00000299427

UniGene: Hs.523454

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