TXNL1 Antibody, FITC conjugated

Code CSB-PA025384HC01HU
Size US$299
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Product Details

Full Product Name Rabbit anti-Homo sapiens (Human) TXNL1 Polyclonal antibody
Uniprot No. O43396
Target Names TXNL1
Alternative Names 32 kDa thioredoxin related protein antibody; 32 kDa thioredoxin-related protein antibody; Thioredoxin like 1 antibody; Thioredoxin like 32kD antibody; Thioredoxin like 32kDa antibody; Thioredoxin like protein 1 antibody; Thioredoxin related 32 kDa protein antibody; Thioredoxin-like protein 1 antibody; TRP 32 antibody; TRP32 antibody; TRxL antibody; TXL 1 antibody; TXL antibody; TXL1 antibody; TXN L1 antibody; TXNL 1 antibody; TXNL antibody; Txnl1 antibody; TXNL1_HUMAN antibody
Raised in Rabbit
Species Reactivity Human
Immunogen Recombinant Human Thioredoxin-like protein 1 protein (2-289AA)
Immunogen Species Homo sapiens (Human)
Conjugate FITC
Clonality Polyclonal
Isotype IgG
Purification Method >95%, Protein G purified
Concentration It differs from different batches. Please contact us to confirm it.
Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form Liquid
Tested Applications ELISA
Protocols ELISA Protocol
Troubleshooting and FAQs Antibody FAQs
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Target Data

Function Active thioredoxin with a redox potential of about -250 mV.
Gene References into Functions
  1. TXNL1 is a novel regulatory molecule that inhibits cisplatin resistance in gastric cancer cells. PMID: 24525731
  2. Distinct protein expression patterns, affecting TXNL1 and HDAC2, distinguish aneuploid with poor prognosis from diploid colorectal cancers. PMID: 21290163
  3. Solution structure of the C-terminal DUF1000 domain of the human thioredoxin-like 1 protein. PMID: 20455272
  4. results imply that TRP-1 is a mammalian thioredoxin and plays as a transcriptional repressor through direct binding to the transcription factor B-Myb PMID: 16231315
  5. TXNL1 acts as an effector of oxidants or a redox sensor by converting redox changes into changes of GDI capacity to capture Rab5, which in turn modulates fluid phase endocytosis PMID: 17987124
  6. Txnl1 is the first example of a direct connection between protein reduction and proteolysis, two major intracellular protein quality control mechanisms. PMID: 19349277
  7. TRP32 was identified as a novel subunit of the 26 S proteasome. PMID: 19349280

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Subcellular Location Cytoplasm, Nucleus
Tissue Specificity Ubiquitous.
Database Links

HGNC: 12436

OMIM: 603049

KEGG: hsa:9352

STRING: 9606.ENSP00000217515

UniGene: Hs.114412

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