Recombinant Bovine GSK3-beta interaction protein(GSKIP)

Product Type Recombinant Protein
Uniprot No. Q0P5A3
Abbreviation GSKIP
Species Bos taurus (Bovine)
Gene Names GSKIP
Protein Names Recommended name: GSK3-beta interaction protein Short name= GSKIP
Storage The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Function A-kinase anchoring protein for GSK3B and PKA that regulates or facilitates their kinase activity towards their targets. The ternary complex enhances Wnt-induced signaling by facilitating the GSK3B- and PKA-induced phosphorylation of beta-catenin leading to beta-catenin degradation and stabilization respectively. Upon cAMP activation, the ternary complex contributes to neuroprotection against oxidative stress-induced apoptosis by facilitating the PKA-induced phosphorylation of DML1 and PKA-induced inactivation of GSK3B. During neurite outgrowth promotes neuron proliferation; while increases beta-catenin-induced transcriptional activity through GSK3B kinase activity inhibition, reduces N-cadherin level to promote cell cycle progression (By similarity). May play a role in cleft palate formation and is required for postnatal life through modulation of the activity of GSK3B during development (By similarity).
Subcellular Location Cytoplasm, Nucleus
Protein Families GSKIP family
Database Links

KEGG: bta:616052

STRING: 9913.ENSBTAP00000026427

UniGene: Bt.107492

Product Details for Different Expression Systems

Product Name Recombinant Bovine GSK3-beta interaction protein(GSKIP),Yeast
Code CSB-YP603908BO
Size Pls inquiry other sizes
Source Yeast
Purity >85% (SDS-PAGE)
Tag Info The following tags are available.
N-terminal His-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Sequence METDCNPMEL SGVSGFEEEA ELNGFEGTDM KDMRLEAEAV VNDVLFAVNT MFVSKTLRCA DDVAYINVET RERNRYCLEL TEAGLRVVGY AFDQVDDHLQ TPYHETVYSL LDTLSPAYRE AFGNALLQRL EALKREGQS
Expression Region 1-139
Protein Description full length protein
Storage Buffer Tris-based buffer,50% glycerol
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Product Name Recombinant Bovine GSK3-beta interaction protein(GSKIP),E.coli
Code CSB-EP603908BO
Size Pls inquiry other sizes
Source E.coli
Purity >85% (SDS-PAGE)
Tag Info The following tags are available.
N-terminal His-tagged and C-terminal Myc-tagged
N-terminal His-SUMO-tagged and C-terminal Myc-tagged
N-terminal His-B2M-tagged and C-terminal Myc-tagged
N-terminal His-GST-tagged and C-terminal Myc-tagged
N-terminal His-tagged
N-terminal His-SUMO-tagged
N-terminal His-B2M-tagged
N-terminal His-GST-tagged
N-terminal GST-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Sequence METDCNPMEL SGVSGFEEEA ELNGFEGTDM KDMRLEAEAV VNDVLFAVNT MFVSKTLRCA DDVAYINVET RERNRYCLEL TEAGLRVVGY AFDQVDDHLQ TPYHETVYSL LDTLSPAYRE AFGNALLQRL EALKREGQS
Expression Region 1-139
Protein Description full length protein
Storage Buffer Tris-based buffer,50% glycerol
Still Have Questions? Leave a Message or Start an on-line Chat
Product Name Recombinant Bovine GSK3-beta interaction protein(GSKIP),Baculovirus
Code CSB-BP603908BO
Size Pls inquiry other sizes
Source Baculovirus
Purity >85% (SDS-PAGE)
Tag Info The following tags are available.
N-terminal His-tagged and C-terminal Myc-tagged
N-terminal His-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Sequence METDCNPMEL SGVSGFEEEA ELNGFEGTDM KDMRLEAEAV VNDVLFAVNT MFVSKTLRCA DDVAYINVET RERNRYCLEL TEAGLRVVGY AFDQVDDHLQ TPYHETVYSL LDTLSPAYRE AFGNALLQRL EALKREGQS
Expression Region 1-139
Protein Description full length protein
Storage Buffer Tris-based buffer,50% glycerol
Still Have Questions? Leave a Message or Start an on-line Chat
Product Name Recombinant Bovine GSK3-beta interaction protein(GSKIP),Mammalian cell
Code CSB-MP603908BO
Size Pls inquiry other sizes
Source Mammalian cell
Purity >85% (SDS-PAGE)
Tag Info The following tags are available.
N-terminal His-tagged and C-terminal Myc-tagged
N-terminal His-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Sequence METDCNPMEL SGVSGFEEEA ELNGFEGTDM KDMRLEAEAV VNDVLFAVNT MFVSKTLRCA DDVAYINVET RERNRYCLEL TEAGLRVVGY AFDQVDDHLQ TPYHETVYSL LDTLSPAYRE AFGNALLQRL EALKREGQS
Expression Region 1-139
Protein Description full length protein
Storage Buffer Tris-based buffer,50% glycerol
Still Have Questions? Leave a Message or Start an on-line Chat

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