Recombinant Bovine Myomesin-1(MYOM1)

Product Type Recombinant Protein
Uniprot No. P80473
Species Bos taurus (Bovine)
Gene Names MYOM1
Protein Names Recommended name: Myomesin-1 Alternative name(s): 190 kDa titin-associated protein Myomesin family member 1
Storage Store at -20°C, for extended storage, conserve at -20°C or -80°C.
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Target Details The giant protein titin, together with its associated proteins, interconnects the major structure of sarcomeres, the M bands and Z discs. The C-terminal end of the titin string extends into the M line, where it binds tightly to M-band constituents of apparent molecular masses of 190 kD (myomesin 1) and 165 kD (myomesin 2). This protein, myomesin 1, like myomesin 2, titin, and other myofibrillar proteins contains structural modules with strong homology to either fibronectin type III (motif I) or immunoglobulin C2 (motif II) domains. Myomesin 1 and myomesin 2 each have a unique N-terminal region followed by 12 modules of motif I or motif II, in the arrangement II-II-I-I-I-I-I-II-II-II-II-II. The two proteins share 50% sequence identity in this repeat-containing region. The head structure formed by these 2 proteins on one end of the titin string extends into the center of the M band. The integrating structure of the sarcomere arises from muscle-specific members of the superfamily of immunoglobulin-like proteins. Alternatively spliced transcript variants encoding different isoforms have been identified.
HGNC 7613
RGD 631436
MGI 1341430
Function Major component of the vertebrate myofibrillar M band. Binds myosin, titin, and light meromyosin. This binding is dose dependent.
Subcellular Location Cytoplasm, myofibril, sarcomere, M line
Tissue Specificity Seems to be expressed in all cardiac and skeletal fibers.
Database Links

UniGene: Bt.37599

Product Details for Different Expression Systems

Product Name Recombinant Bovine Myomesin-1(MYOM1),Yeast
Code CSB-YP015361BO
Size Pls inquiry other sizes
Source Yeast
Purity >85% (SDS-PAGE)
Tag Info The following tags are available.
N-terminal His-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Sequence QSMSTLHQEE AFEKADQLSL KKTLEETEAF HKKLNEDHLL HAPEPVIKPG TAYKNQVPIN VQAHPGKYII ESRYGVHTLE INDDTRFHSG ASTLPPSXYA SRFEIHFQPE IQXYRNGVPI DAEXXGAPAI PKYNDYIIIT XKQPAVDGGS PILGYFIDVG IGXPSRVSEP VAALDPAEKA RLKSRPSAPX TGQIIVTEEE PSEEAGTENX QRVNTELPVK XSNNAGVXEP EETGGAEITG YYVNYREVID GVPGRXREAN IKAISDEAYK XEEXTIAVPG PPHMTFKNRA RVVGGLPDVV TIQEGKLLAS DEHXNLKYGS EISDFTVSVF IPEEEARSVA
Expression Region 1-340
Protein Description Full length protein
Storage Buffer Tris-based buffer,50% glycerol
Still Have Questions? Leave a Message or Start an on-line Chat
Product Name Recombinant Bovine Myomesin-1(MYOM1),E.coli
Code CSB-EP015361BO
Size Pls inquiry other sizes
Source E.coli
Purity >85% (SDS-PAGE)
Tag Info The following tags are available.
N-terminal His-tagged and C-terminal Myc-tagged
N-terminal His-SUMO-tagged and C-terminal Myc-tagged
N-terminal His-B2M-tagged and C-terminal Myc-tagged
N-terminal His-GST-tagged and C-terminal Myc-tagged
N-terminal His-tagged
N-terminal His-SUMO-tagged
N-terminal His-B2M-tagged
N-terminal His-GST-tagged
N-terminal GST-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Sequence QSMSTLHQEE AFEKADQLSL KKTLEETEAF HKKLNEDHLL HAPEPVIKPG TAYKNQVPIN VQAHPGKYII ESRYGVHTLE INDDTRFHSG ASTLPPSXYA SRFEIHFQPE IQXYRNGVPI DAEXXGAPAI PKYNDYIIIT XKQPAVDGGS PILGYFIDVG IGXPSRVSEP VAALDPAEKA RLKSRPSAPX TGQIIVTEEE PSEEAGTENX QRVNTELPVK XSNNAGVXEP EETGGAEITG YYVNYREVID GVPGRXREAN IKAISDEAYK XEEXTIAVPG PPHMTFKNRA RVVGGLPDVV TIQEGKLLAS DEHXNLKYGS EISDFTVSVF IPEEEARSVA
Expression Region 1-340
Protein Description Full length protein
Storage Buffer Tris-based buffer,50% glycerol
Still Have Questions? Leave a Message or Start an on-line Chat
Product Name Recombinant Bovine Myomesin-1(MYOM1),Baculovirus
Code CSB-BP015361BO
Size Pls inquiry other sizes
Source Baculovirus
Purity >85% (SDS-PAGE)
Tag Info The following tags are available.
N-terminal His-tagged and C-terminal Myc-tagged
N-terminal His-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Sequence QSMSTLHQEE AFEKADQLSL KKTLEETEAF HKKLNEDHLL HAPEPVIKPG TAYKNQVPIN VQAHPGKYII ESRYGVHTLE INDDTRFHSG ASTLPPSXYA SRFEIHFQPE IQXYRNGVPI DAEXXGAPAI PKYNDYIIIT XKQPAVDGGS PILGYFIDVG IGXPSRVSEP VAALDPAEKA RLKSRPSAPX TGQIIVTEEE PSEEAGTENX QRVNTELPVK XSNNAGVXEP EETGGAEITG YYVNYREVID GVPGRXREAN IKAISDEAYK XEEXTIAVPG PPHMTFKNRA RVVGGLPDVV TIQEGKLLAS DEHXNLKYGS EISDFTVSVF IPEEEARSVA
Expression Region 1-340
Protein Description Full length protein
Storage Buffer Tris-based buffer,50% glycerol
Still Have Questions? Leave a Message or Start an on-line Chat
Product Name Recombinant Bovine Myomesin-1(MYOM1),Mammalian cell
Code CSB-MP015361BO
Size Pls inquiry other sizes
Source Mammalian cell
Purity >85% (SDS-PAGE)
Tag Info The following tags are available.
N-terminal His-tagged and C-terminal Myc-tagged
N-terminal His-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Sequence QSMSTLHQEE AFEKADQLSL KKTLEETEAF HKKLNEDHLL HAPEPVIKPG TAYKNQVPIN VQAHPGKYII ESRYGVHTLE INDDTRFHSG ASTLPPSXYA SRFEIHFQPE IQXYRNGVPI DAEXXGAPAI PKYNDYIIIT XKQPAVDGGS PILGYFIDVG IGXPSRVSEP VAALDPAEKA RLKSRPSAPX TGQIIVTEEE PSEEAGTENX QRVNTELPVK XSNNAGVXEP EETGGAEITG YYVNYREVID GVPGRXREAN IKAISDEAYK XEEXTIAVPG PPHMTFKNRA RVVGGLPDVV TIQEGKLLAS DEHXNLKYGS EISDFTVSVF IPEEEARSVA
Expression Region 1-340
Protein Description Full length protein
Storage Buffer Tris-based buffer,50% glycerol
Still Have Questions? Leave a Message or Start an on-line Chat

Most popular with customers

Newsletters

Get all the latest information on Events, Sales and Offers. Sign up for newsletter today.

Copyright © 2007-2018 www.cusabio.com CUSABIO TECHNOLOGY LLC All Rights Reserved.