Recombinant Callithrix jacchus Cyclin-dependent kinase 14(CDK14)

Product Type Recombinant Protein
Uniprot No. B0VXE8
Species Callithrix jacchus (White-tufted-ear marmoset)
Gene Names CDK14
Protein Names Recommended name: Cyclin-dependent kinase 14 EC= 2.7.11.22 Alternative name(s): Cell division protein kinase 14
Storage The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Function Serine/threonine-protein kinase involved in the control of the eukaryotic cell cycle, whose activity is controlled by an associated cyclin. Acts as a cell-cycle regulator of Wnt signaling pathway during G2/M phase by mediating the phosphorylation of LRP6 at 'Ser-1490', leading to the activation of the Wnt signaling pathway. Acts as a regulator of cell cycle progression and cell proliferation via its interaction with CCDN3. Phosphorylates RB1 in vitro, however the relevance of such result remains to be confirmed in vivo. May also play a role in meiosis, neuron differentiation and may indirectly act as a negative regulator of insulin-responsive glucose transport (By similarity).
Subcellular Location Cell membrane, Peripheral membrane protein, Cytoplasm, Nucleus
Protein Families Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily
Database Links

KEGG: cjc:100391008

STRING: 9483.ENSCJAP00000026131

Product Details for Different Expression Systems

Product Name Recombinant Callithrix jacchus Cyclin-dependent kinase 14(CDK14),Yeast
Code CSB-YP535223CYL
Size Pls inquiry other sizes
Source Yeast
Purity >85% (SDS-PAGE)
Tag Info The following tags are available.
N-terminal His-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Sequence MSTRNCQGMD SVIKPLDTIP EDKKVRVQRT QSTFDPFEKP TNQVKRVHSE NNACINFKTS STGKESPKVR RHSSPSSPTS PKFGKADSYE KLEKLGEGSY ATVYKGKSKV NGKLVALKVI RLQEEEGTPF TAIREASLLK GLKHANIVLL HDIIHTKETL TLVFEYVHTD LCQYMDKHPG GLHPDNVKLF LFQLLRGLSY IHQRYILHRD LKPQNLLISD TGELKLADFG LARAKSVPSH TYSNEVVTLW YRPPDVLLGS TEYSTCLDMW GVGCIFVEMI QGVAAFPGMK DIQDQLERIF LVLGTPNEDT WPGVHSLPHF KPERFTLYSS KNLRQAWNKL SYVNHAEDLA SKLLQCSPKN RLSAQAALSH EYFSDLPPRL WELTDMSSIF TVPNVRLQPE AGESMRAFGK NNSYGKSLSN SKH
Expression Region 1-423
Protein Description full length protein
Storage Buffer Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
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Product Name Recombinant Callithrix jacchus Cyclin-dependent kinase 14(CDK14),E.coli
Code CSB-EP535223CYL
Size Pls inquiry other sizes
Source E.coli
Purity >85% (SDS-PAGE)
Tag Info The following tags are available.
N-terminal His-tagged and C-terminal Myc-tagged
N-terminal His-SUMO-tagged and C-terminal Myc-tagged
N-terminal His-B2M-tagged and C-terminal Myc-tagged
N-terminal His-GST-tagged and C-terminal Myc-tagged
N-terminal His-tagged
N-terminal His-SUMO-tagged
N-terminal His-B2M-tagged
N-terminal His-GST-tagged
N-terminal GST-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Sequence MSTRNCQGMD SVIKPLDTIP EDKKVRVQRT QSTFDPFEKP TNQVKRVHSE NNACINFKTS STGKESPKVR RHSSPSSPTS PKFGKADSYE KLEKLGEGSY ATVYKGKSKV NGKLVALKVI RLQEEEGTPF TAIREASLLK GLKHANIVLL HDIIHTKETL TLVFEYVHTD LCQYMDKHPG GLHPDNVKLF LFQLLRGLSY IHQRYILHRD LKPQNLLISD TGELKLADFG LARAKSVPSH TYSNEVVTLW YRPPDVLLGS TEYSTCLDMW GVGCIFVEMI QGVAAFPGMK DIQDQLERIF LVLGTPNEDT WPGVHSLPHF KPERFTLYSS KNLRQAWNKL SYVNHAEDLA SKLLQCSPKN RLSAQAALSH EYFSDLPPRL WELTDMSSIF TVPNVRLQPE AGESMRAFGK NNSYGKSLSN SKH
Expression Region 1-423
Protein Description full length protein
Storage Buffer Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
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Product Name Recombinant Callithrix jacchus Cyclin-dependent kinase 14(CDK14),Baculovirus
Code CSB-BP535223CYL
Size Pls inquiry other sizes
Source Baculovirus
Purity >85% (SDS-PAGE)
Tag Info The following tags are available.
N-terminal His-tagged and C-terminal Myc-tagged
N-terminal His-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Sequence MSTRNCQGMD SVIKPLDTIP EDKKVRVQRT QSTFDPFEKP TNQVKRVHSE NNACINFKTS STGKESPKVR RHSSPSSPTS PKFGKADSYE KLEKLGEGSY ATVYKGKSKV NGKLVALKVI RLQEEEGTPF TAIREASLLK GLKHANIVLL HDIIHTKETL TLVFEYVHTD LCQYMDKHPG GLHPDNVKLF LFQLLRGLSY IHQRYILHRD LKPQNLLISD TGELKLADFG LARAKSVPSH TYSNEVVTLW YRPPDVLLGS TEYSTCLDMW GVGCIFVEMI QGVAAFPGMK DIQDQLERIF LVLGTPNEDT WPGVHSLPHF KPERFTLYSS KNLRQAWNKL SYVNHAEDLA SKLLQCSPKN RLSAQAALSH EYFSDLPPRL WELTDMSSIF TVPNVRLQPE AGESMRAFGK NNSYGKSLSN SKH
Expression Region 1-423
Protein Description full length protein
Storage Buffer Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Still Have Questions? Leave a Message or Start an on-line Chat
Product Name Recombinant Callithrix jacchus Cyclin-dependent kinase 14(CDK14),Mammalian cell
Code CSB-MP535223CYL
Size Pls inquiry other sizes
Source Mammalian cell
Purity >85% (SDS-PAGE)
Tag Info The following tags are available.
N-terminal His-tagged and C-terminal Myc-tagged
N-terminal His-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Sequence MSTRNCQGMD SVIKPLDTIP EDKKVRVQRT QSTFDPFEKP TNQVKRVHSE NNACINFKTS STGKESPKVR RHSSPSSPTS PKFGKADSYE KLEKLGEGSY ATVYKGKSKV NGKLVALKVI RLQEEEGTPF TAIREASLLK GLKHANIVLL HDIIHTKETL TLVFEYVHTD LCQYMDKHPG GLHPDNVKLF LFQLLRGLSY IHQRYILHRD LKPQNLLISD TGELKLADFG LARAKSVPSH TYSNEVVTLW YRPPDVLLGS TEYSTCLDMW GVGCIFVEMI QGVAAFPGMK DIQDQLERIF LVLGTPNEDT WPGVHSLPHF KPERFTLYSS KNLRQAWNKL SYVNHAEDLA SKLLQCSPKN RLSAQAALSH EYFSDLPPRL WELTDMSSIF TVPNVRLQPE AGESMRAFGK NNSYGKSLSN SKH
Expression Region 1-423
Protein Description full length protein
Storage Buffer Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Still Have Questions? Leave a Message or Start an on-line Chat

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