Recombinant Chicken Gallinacin-3 (GAL3)

Code CSB-YP887614CH
MSDS
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Source Yeast
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Code CSB-EP887614CH
MSDS
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Source E.coli
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Code CSB-EP887614CH-B
MSDS
Size Pls inquire
Source E.coli
Conjugate Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code CSB-BP887614CH
MSDS
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Source Baculovirus
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Code CSB-MP887614CH
MSDS
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Source Mammalian cell
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Product Details

Purity
>85% (SDS-PAGE)
Target Names
GAL3
Uniprot No.
Alternative Names
GAL3; Gallinacin-3; Gal-3; Beta-defensin 3
Species
Gallus gallus (Chicken)
Expression Region
23-80
Target Protein Sequence
TQCRIRGG FCRVGSCRFP HIAIGKCATF ISCCGRAYEV DALNSVRTSP WLLAPGNNPH
Protein Length
Full Length of Mature Protein
Tag Info
Tag type will be determined during the manufacturing process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form
Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization
Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet
Please contact us to get it.

Customer Reviews and Q&A

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Target Background

Function
Has bactericidal activity.
Gene References into Functions
  1. Data suggest that DEFB1 and DEFB3 are involved in mechanisms by which the vaginal mucosa forms a more efficient defense system against bacterial infection; proinflammatory cytokines induce DEFB1 and DEFB3 in vagina mucosa cells. PMID: 23625580
  2. potent adjuvant effects of beta-defensin-1 when genetically fused with infectious bursal disease virus VP2 gene PMID: 20334934
  3. The chicken genome encodes only beta-defensins. The 13 chicken beta-defensin genes are clustered densely within a 86-Kb distance on the chromosome 3q3.5-q3.7. The deduced peptides share the characteristic defensin motif. PMID: 15310403
  4. mRNA expression of Gal-1, -2 and -3 in the vagina of laying hens increases with age but decreases in the regressed oviduct during the non-laying phase, and may increase in response to Salmonella enteritidis (SE) and lipopolysaccharide PMID: 16394622
  5. AvBD-3 is synthesized by late stage of spermatids in the testis, and this molecule is retained by the sperm during the passage of male reproductive tract, and even in the sperm storage tubules of oviduct. PMID: 19038823
  6. intestinal epithelium express beta-defensin antimicrobial peptides that may play a role in immunoprotection against Salmonella Enteritidis. PMID: 19539093

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Subcellular Location
Secreted. Cytoplasmic granule.
Protein Families
Beta-defensin family
Tissue Specificity
Strongly expressed in the tongue, bone marrow, bursa of Fabricius and trachea. Also expressed in skin, esophagus and air sacs. Weak expression in the large intestine, kidney and ovary. Expressed in the vagina and ovarian stroma, but not in the ovarian fol
Database Links
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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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