Recombinant Chicken Homeobox protein DLX-5 (DLX5)

Code CSB-YP006956CH
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Source Yeast
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Code CSB-EP006956CH
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Source E.coli
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Code CSB-EP006956CH-B
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Source E.coli
Conjugate Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code CSB-BP006956CH
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Source Baculovirus
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Code CSB-MP006956CH
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Source Mammalian cell
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Product Details

Purity
>85% (SDS-PAGE)
Target Names
DLX5
Uniprot No.
Alternative Names
DLX5; DLX-5Homeobox protein DLX-5; cDlx
Species
Gallus gallus (Chicken)
Expression Region
1-286
Target Protein Sequence
MTAVFDRRVP GIRSSDFQPP FQSAAAMHHP SQESPTLPES SATDSDYYSP TGAAPHGYCS PTSASYGKAL NPYQYQYGMN GSAGTYPAKA YADYGYGSPY HQYGGAYGRG QSSAGQPEKE VAEPEVRMVN GKPKKVRKPR TIYSSFQLAA LQRRFQKTQY LALPERAELA ASLGLTQTQV KIWFQNKRSK IKKIMKNGEM PPEHSPSSSD PMACNSPQSP AVWEPQGSSR SLGHHGHGHP PAANPSPGSY LESPSAWYPA ASPLGSHLQP HGSLQHPLAL PSGTIY
Protein Length
Full length protein
Tag Info
Tag type will be determined during the manufacturing process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form
Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization
Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet
Please contact us to get it.

Customer Reviews and Q&A

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Target Background

Function
Transcriptional factor involved in bone development. Could be involved in apical ectodermal ridge activity, pattern formation, and cartilage differentiation. Binds to DNA.
Gene References into Functions
  1. We find Dlx5 and Dlx6 to be quantitatively indistinguishable on a variety of natural cis-regulatory sequences in a heterologous cellular context but observed quantitatively different transcriptional outputs in cells that normally express these genes, suggesting differential interactions with co-evolved co-activators. PMID: 27416760
  2. Inner ear expression patterns of Dlx3, Dlx5, and Dlx6 were examined during the first 7 days of chicken embryonic development. PMID: 15672396
  3. ectethmoid formation depends upon Dlx5 and Dlx6 expression in a restricted ectodermal territory of the anterior neural folds PMID: 21270050
  4. Dlx5 has roles during multiple stages of chondrocyte differentiation and is a general regulator of differentiation in the skeleton PMID: 12895028
  5. investigated the domain requirements and transcriptional activities associated with Dlx5- and Dlx6-mediated chondrogenesis PMID: 17027239
  6. Dlx5 and 6 genes may be involved in specification of the elbow joint and/or in providing positional information that specifies the site at which the elbow joint will form PMID: 17051482
  7. Dlx5 and related Dlx factors play a pivotal role in the onset of differentiation of chick calvaria osteoblasts. PMID: 17335796

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Subcellular Location
Nucleus.
Protein Families
Distal-less homeobox family
Database Links
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