Recombinant Chicken Protein Wnt-4(WNT4)

Product Type Recombinant Protein
Uniprot No. P49337
Species Gallus gallus (Chicken)
Gene Names WNT4
Protein Names Recommended name: Protein Wnt-4
Storage Store at -20°C, for extended storage, conserve at -20°C or -80°C.
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Target Details The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family, and is the first signaling molecule shown to influence the sex-determination cascade. It encodes a protein which shows 98% amino acid identity to the Wnt4 protein of mouse and rat. This gene and a nuclear receptor known to antagonize the testis-determining factor play a concerted role in both the control of female development and the prevention of testes formation. This gene and another two family members, WNT2 and WNT7B, may be associated with abnormal proliferation in breast tissue. Mutations in this gene can result in Rokitansky-Kuster-Hauser syndrome and in SERKAL syndrome.
Function Ligand for members of the frizzled family of seven transmembrane receptors. May be an intracellular signaling molecule involved in segmentation of the forebrain into the neuromere D2 and in differentiation of the dorsal region of the spinal cord. Is likely to signal over only few cell diameters.
Subcellular Location Secreted, extracellular space, extracellular matrix
Protein Families Wnt family
Tissue Specificity Predominantly expressed in the diencephalon neuromere D2.
Database Links

KEGG: gga:395561

STRING: 9031.ENSGALP00000007633

UniGene: Gga.305

Pathway Hippo signaling pathway
Melanogenesis
mTOR signaling pathway
Wnt signaling pathway
Signaling pathways regulating pluripotency of stem cells

Product Details for Different Expression Systems

Product Name Recombinant Chicken Protein Wnt-4(WNT4),Yeast
Code CSB-YP026137CH
Size Pls inquiry other sizes
Source Yeast
Purity >85% (SDS-PAGE)
Tag Info The following tags are available.
N-terminal His-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Sequence SNWLYLAK LSSVGSISEE ETCEKLKGLI QRQVQMCKRN LEVMDSVRRG AQLAIEECQY QFRNRRWNCS TLDTLPVFGK VVTQGTREAA FVYAISSAGV AFAVTRACSS GELDKCGCDR TVQGGSPQGF QWSGCSDNIA YGVAFSQSFV DVRERSKGAS SNRALMNLHN NEAGRKAILN NMRVECKCHG VSGSCEFKTC WKAMPPFRKV GNVLKEKFDG ATEVEQSEIG STKVLVPKNS QFKPHTDEDL VYLDSSPDFC DHDLKNGVLG TSGRQCNKTS KAIDGCELMC CGRGFHTDEV EVVERCSCKF HWCCSVKCKP CHRVVEIHTC R
Expression Region 23-351
Protein Description Full Length of Mature Protein
Storage Buffer Tris-based buffer,50% glycerol
Still Have Questions? Leave a Message or Start an on-line Chat
Product Name Recombinant Chicken Protein Wnt-4(WNT4),E.coli
Code CSB-EP026137CH
Size Pls inquiry other sizes
Source E.coli
Purity >85% (SDS-PAGE)
Tag Info The following tags are available.
N-terminal His-tagged and C-terminal Myc-tagged
N-terminal His-SUMO-tagged and C-terminal Myc-tagged
N-terminal His-B2M-tagged and C-terminal Myc-tagged
N-terminal His-GST-tagged and C-terminal Myc-tagged
N-terminal His-tagged
N-terminal His-SUMO-tagged
N-terminal His-B2M-tagged
N-terminal His-GST-tagged
N-terminal GST-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Sequence SNWLYLAK LSSVGSISEE ETCEKLKGLI QRQVQMCKRN LEVMDSVRRG AQLAIEECQY QFRNRRWNCS TLDTLPVFGK VVTQGTREAA FVYAISSAGV AFAVTRACSS GELDKCGCDR TVQGGSPQGF QWSGCSDNIA YGVAFSQSFV DVRERSKGAS SNRALMNLHN NEAGRKAILN NMRVECKCHG VSGSCEFKTC WKAMPPFRKV GNVLKEKFDG ATEVEQSEIG STKVLVPKNS QFKPHTDEDL VYLDSSPDFC DHDLKNGVLG TSGRQCNKTS KAIDGCELMC CGRGFHTDEV EVVERCSCKF HWCCSVKCKP CHRVVEIHTC R
Expression Region 23-351
Protein Description Full Length of Mature Protein
Storage Buffer Tris-based buffer,50% glycerol
Still Have Questions? Leave a Message or Start an on-line Chat
Product Name Recombinant Chicken Protein Wnt-4(WNT4),Baculovirus
Code CSB-BP026137CH
Size Pls inquiry other sizes
Source Baculovirus
Purity >85% (SDS-PAGE)
Tag Info The following tags are available.
N-terminal His-tagged and C-terminal Myc-tagged
N-terminal His-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Sequence SNWLYLAK LSSVGSISEE ETCEKLKGLI QRQVQMCKRN LEVMDSVRRG AQLAIEECQY QFRNRRWNCS TLDTLPVFGK VVTQGTREAA FVYAISSAGV AFAVTRACSS GELDKCGCDR TVQGGSPQGF QWSGCSDNIA YGVAFSQSFV DVRERSKGAS SNRALMNLHN NEAGRKAILN NMRVECKCHG VSGSCEFKTC WKAMPPFRKV GNVLKEKFDG ATEVEQSEIG STKVLVPKNS QFKPHTDEDL VYLDSSPDFC DHDLKNGVLG TSGRQCNKTS KAIDGCELMC CGRGFHTDEV EVVERCSCKF HWCCSVKCKP CHRVVEIHTC R
Expression Region 23-351
Protein Description Full Length of Mature Protein
Storage Buffer Tris-based buffer,50% glycerol
Still Have Questions? Leave a Message or Start an on-line Chat
Product Name Recombinant Chicken Protein Wnt-4(WNT4),Mammalian cell
Code CSB-MP026137CH
Size Pls inquiry other sizes
Source Mammalian cell
Purity >85% (SDS-PAGE)
Tag Info The following tags are available.
N-terminal His-tagged and C-terminal Myc-tagged
N-terminal His-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Sequence SNWLYLAK LSSVGSISEE ETCEKLKGLI QRQVQMCKRN LEVMDSVRRG AQLAIEECQY QFRNRRWNCS TLDTLPVFGK VVTQGTREAA FVYAISSAGV AFAVTRACSS GELDKCGCDR TVQGGSPQGF QWSGCSDNIA YGVAFSQSFV DVRERSKGAS SNRALMNLHN NEAGRKAILN NMRVECKCHG VSGSCEFKTC WKAMPPFRKV GNVLKEKFDG ATEVEQSEIG STKVLVPKNS QFKPHTDEDL VYLDSSPDFC DHDLKNGVLG TSGRQCNKTS KAIDGCELMC CGRGFHTDEV EVVERCSCKF HWCCSVKCKP CHRVVEIHTC R
Expression Region 23-351
Protein Description Full Length of Mature Protein
Storage Buffer Tris-based buffer,50% glycerol
Still Have Questions? Leave a Message or Start an on-line Chat

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