Recombinant Chicken Serotonin N-acetyltransferase(AANAT)

Product Type Recombinant Protein
Uniprot No. P79774
Species Gallus gallus (Chicken)
Gene Names AANAT
Protein Names Recommended name: Serotonin N-acetyltransferase Short name= Serotonin acetylase EC= 2.3.1.87 Alternative name(s): Aralkylamine N-acetyltransferase Short name= AA-NAT
Storage Store at -20°C, for extended storage, conserve at -20°C or -80°C.
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Target Details This protein belongs to the acetyltransferase superfamily. It is the penultimate enzyme in melatonin synthesis and controls the night/day rhythm in melatonin production in the vertebrate pineal gland. Melatonin is essential for the function of the circadian clock that influences activity and sleep. This enzyme is regulated by cAMP-dependent phosphorylation that promotes its interaction with 14-3-3 proteins and thus protects the enzyme against proteasomal degradation. This gene may contribute to numerous genetic diseases such as delayed sleep phase syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Function Catalyzes the N-acetylation of serotonin into N-acetylserotonin.
Subcellular Location Cytoplasm
Protein Families Acetyltransferase family, AANAT subfamily
Tissue Specificity Expressed in follicular pineal cells and retinal photoreceptors with five times more expression in the pineal gland.
Database Links

KEGG: gga:396066

STRING: 9031.ENSGALP00000003020

UniGene: Gga.634

Product Details for Different Expression Systems

Product Name Recombinant Chicken Serotonin N-acetyltransferase(AANAT),Yeast
Code CSB-YP001022CH
Size Pls inquiry other sizes
Source Yeast
Purity >85% (SDS-PAGE)
Tag Info The following tags are available.
N-terminal His-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Sequence MPVLGAVPFL KPTPLQGPRN SPGRQRRHTL PASEFRCLSP EDAVSVFEIE REAFISVSGD CPLHLDEIRH FLTLCPELSL GWFEEGRLVA FIIGSLWDQD RLSQAALTLH NPRGTAVHIH VLAVHRTFRQ QGKGSILMWR YLQYLRCLPC ARRAVLMCED FLVPFYEKCG FVAVGPCQVT VGTLAFTEMQ HEVRGHAFMR RNSGC
Expression Region 1-205
Protein Description Full length protein
Storage Buffer Tris-based buffer,50% glycerol
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Product Name Recombinant Chicken Serotonin N-acetyltransferase(AANAT),E.coli
Code CSB-EP001022CH
Size Pls inquiry other sizes
Source E.coli
Purity >85% (SDS-PAGE)
Tag Info The following tags are available.
N-terminal His-tagged and C-terminal Myc-tagged
N-terminal His-SUMO-tagged and C-terminal Myc-tagged
N-terminal His-B2M-tagged and C-terminal Myc-tagged
N-terminal His-GST-tagged and C-terminal Myc-tagged
N-terminal His-tagged
N-terminal His-SUMO-tagged
N-terminal His-B2M-tagged
N-terminal His-GST-tagged
N-terminal GST-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Sequence MPVLGAVPFL KPTPLQGPRN SPGRQRRHTL PASEFRCLSP EDAVSVFEIE REAFISVSGD CPLHLDEIRH FLTLCPELSL GWFEEGRLVA FIIGSLWDQD RLSQAALTLH NPRGTAVHIH VLAVHRTFRQ QGKGSILMWR YLQYLRCLPC ARRAVLMCED FLVPFYEKCG FVAVGPCQVT VGTLAFTEMQ HEVRGHAFMR RNSGC
Expression Region 1-205
Protein Description Full length protein
Storage Buffer Tris-based buffer,50% glycerol
Still Have Questions? Leave a Message or Start an on-line Chat
Product Name Recombinant Chicken Serotonin N-acetyltransferase(AANAT),Baculovirus
Code CSB-BP001022CH
Size Pls inquiry other sizes
Source Baculovirus
Purity >85% (SDS-PAGE)
Tag Info The following tags are available.
N-terminal His-tagged and C-terminal Myc-tagged
N-terminal His-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Sequence MPVLGAVPFL KPTPLQGPRN SPGRQRRHTL PASEFRCLSP EDAVSVFEIE REAFISVSGD CPLHLDEIRH FLTLCPELSL GWFEEGRLVA FIIGSLWDQD RLSQAALTLH NPRGTAVHIH VLAVHRTFRQ QGKGSILMWR YLQYLRCLPC ARRAVLMCED FLVPFYEKCG FVAVGPCQVT VGTLAFTEMQ HEVRGHAFMR RNSGC
Expression Region 1-205
Protein Description Full length protein
Storage Buffer Tris-based buffer,50% glycerol
Still Have Questions? Leave a Message or Start an on-line Chat
Product Name Recombinant Chicken Serotonin N-acetyltransferase(AANAT),Mammalian cell
Code CSB-MP001022CH
Size Pls inquiry other sizes
Source Mammalian cell
Purity >85% (SDS-PAGE)
Tag Info The following tags are available.
N-terminal His-tagged and C-terminal Myc-tagged
N-terminal His-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Sequence MPVLGAVPFL KPTPLQGPRN SPGRQRRHTL PASEFRCLSP EDAVSVFEIE REAFISVSGD CPLHLDEIRH FLTLCPELSL GWFEEGRLVA FIIGSLWDQD RLSQAALTLH NPRGTAVHIH VLAVHRTFRQ QGKGSILMWR YLQYLRCLPC ARRAVLMCED FLVPFYEKCG FVAVGPCQVT VGTLAFTEMQ HEVRGHAFMR RNSGC
Expression Region 1-205
Protein Description Full length protein
Storage Buffer Tris-based buffer,50% glycerol
Still Have Questions? Leave a Message or Start an on-line Chat

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