Recombinant Chicken Telomeric repeat-binding factor 2-interacting protein 1 (TERF2IP)

Code CSB-YP749221CH
MSDS
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Source Yeast
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Code CSB-EP749221CH
MSDS
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Source E.coli
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Code CSB-EP749221CH-B
MSDS
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Source E.coli
Conjugate Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code CSB-BP749221CH
MSDS
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Source Baculovirus
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Code CSB-MP749221CH
MSDS
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Source Mammalian cell
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Product Details

Purity
>85% (SDS-PAGE)
Target Names
TERF2IP
Uniprot No.
Alternative Names
TERF2IP; RAP1; Telomeric repeat-binding factor 2-interacting protein 1; TERF2-interacting telomeric protein 1; TRF2-interacting telomeric protein 1; Repressor/activator protein 1 homolog; RAP1 homolog; cRAP1
Species
Gallus gallus (Chicken)
Expression Region
1-329
Target Protein Sequence
MAAPPRKVFV WEDGTPMRFY IRPGMAKLRL APLLLAGGAG LCRVQEPGAV HLVQPGEPAP DGAVSTDYVV ACVESQRRLP LDLYRHSGPA PLAASPRGRL PFTEAEDAAL LRAVRERSGA PRVSGTALWK ELECTGLTRH SWQAMRDRYL RHLRPLHRES QQTEEAAAPM GIFEAANREF ESSESGSDTS DTPDELPLQN GEGTFPLEAA SGLQTGLDDC ALPAAQGENK QTNTFSDSSK AEEAAQIIQH FMEEFHTDLL TVTQALLKNS GEVEATSYYL HAGQRLDGYP VWSREDDLEL QKDDEDVRSK LIAKFGAENV ARRVAFRKS
Protein Length
full length protein
Tag Info
Tag type will be determined during the manufacturing process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form
Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization
Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet
Please contact us to get it.

Customer Reviews and Q&A

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Target Background

Function
Acts both as a regulator of telomere function and as a transcription regulator. Involved in the regulation of telomere length and protection as a component of the shelterin complex (telosome). Does not bind DNA directly: recruited to telomeric double-stranded 5'-TTAGGG-3' repeats via its interaction with terf2. Independently of its function in telomeres, also acts as a transcription regulator: recruited to extratelomeric 5'-TTAGGG-3' sites via its association with terf2 or other factors, and regulates gene expression.
Gene References into Functions
  1. JunD and AP-1 antagonize the induction of DAPK1 to promote the survival of v-Src-transformed cells. PMID: 27795443
Subcellular Location
Nucleus. Chromosome, telomere.
Protein Families
RAP1 family
Database Links
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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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