Recombinant Chicken Thyroid hormone receptor beta(THRB)

Product Type Recombinant Protein
Uniprot No. P68306
Species Gallus gallus (Chicken)
Gene Names THRB
Protein Names Recommended name: Thyroid hormone receptor beta Alternative name(s): Nuclear receptor subfamily 1 group A member 2
Storage Store at -20°C, for extended storage, conserve at -20°C or -80°C.
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Target Details This protein is a nuclear hormone receptor for triiodothyronine. It is one of the several receptors for thyroid hormone, and has been shown to mediate the biological activities of thyroid hormone. Knockout studies in mice suggest that the different receptors, while having certain extent of redundancy, may mediate different functions of thyroid hormone. Mutations in this gene are known to be a cause of generalized thyroid hormone resistance (GTHR), a syndrome characterized by goiter and high levels of circulating thyroid hormone (T3-T4), with normal or slightly elevated thyroid stimulating hormone (TSH). Several alternatively spliced transcript variants encoding the same protein have been observed for this gene.
Function Nuclear hormone receptor that can act as a repressor or activator of transcription. High affinity receptor for thyroid hormones, including triiodothyronine and thyroxine.
Subcellular Location Nucleus
Protein Families Nuclear hormone receptor family, NR1 subfamily
Database Links

KEGG: gga:396431

STRING: 9031.ENSGALP00000018402

UniGene: Gga.609

Product Details for Different Expression Systems

Product Name Recombinant Chicken Thyroid hormone receptor beta(THRB),Yeast
Code CSB-YP023514CH
Size Pls inquiry other sizes
Source Yeast
Purity >85% (SDS-PAGE)
Tag Info The following tags are available.
N-terminal His-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Sequence MSGYIPSYLD KDELCVVCGD KATGYHYRCI TCEGCKGFFR RTIQKNLHPT YSCKYEGKCV IDKVTRNQCQ ECRFKKCIFV GMATDLVLDD SKRLAKRKLI EENREKRRRE ELQKTIGHKP EPTDEEWELI KIVTEAHVAT NAQGSHWKQK RKFLPEDIGQ APIVNAPEGG KVDLEAFSQF TKIITPAITR VVDFAKKLPM FCELPCEDQI ILLKGCCMEI MSLRAAVRYD PESETLTLNG EMAVTRGQLK NGGLGVVSDA IFDLGMSLSS FNLDDTEVAL LQAVLLMSSD RPGLVCVERI EKCQEGFLLA FEHYINYRKH HVAHFWPKLL MKVTDLRMIG ACHASRFLHM KVECPTELFP PLFLEVFED
Expression Region 1-369
Protein Description Full length protein
Storage Buffer Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
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Product Name Recombinant Chicken Thyroid hormone receptor beta(THRB),E.coli
Code CSB-EP023514CH
Size Pls inquiry other sizes
Source E.coli
Purity >85% (SDS-PAGE)
Tag Info The following tags are available.
N-terminal His-tagged and C-terminal Myc-tagged
N-terminal His-SUMO-tagged and C-terminal Myc-tagged
N-terminal His-B2M-tagged and C-terminal Myc-tagged
N-terminal His-GST-tagged and C-terminal Myc-tagged
N-terminal His-tagged
N-terminal His-SUMO-tagged
N-terminal His-B2M-tagged
N-terminal His-GST-tagged
N-terminal GST-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Sequence MSGYIPSYLD KDELCVVCGD KATGYHYRCI TCEGCKGFFR RTIQKNLHPT YSCKYEGKCV IDKVTRNQCQ ECRFKKCIFV GMATDLVLDD SKRLAKRKLI EENREKRRRE ELQKTIGHKP EPTDEEWELI KIVTEAHVAT NAQGSHWKQK RKFLPEDIGQ APIVNAPEGG KVDLEAFSQF TKIITPAITR VVDFAKKLPM FCELPCEDQI ILLKGCCMEI MSLRAAVRYD PESETLTLNG EMAVTRGQLK NGGLGVVSDA IFDLGMSLSS FNLDDTEVAL LQAVLLMSSD RPGLVCVERI EKCQEGFLLA FEHYINYRKH HVAHFWPKLL MKVTDLRMIG ACHASRFLHM KVECPTELFP PLFLEVFED
Expression Region 1-369
Protein Description Full length protein
Storage Buffer Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Still Have Questions? Leave a Message or Start an on-line Chat
Product Name Recombinant Chicken Thyroid hormone receptor beta(THRB),Baculovirus
Code CSB-BP023514CH
Size Pls inquiry other sizes
Source Baculovirus
Purity >85% (SDS-PAGE)
Tag Info The following tags are available.
N-terminal His-tagged and C-terminal Myc-tagged
N-terminal His-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Sequence MSGYIPSYLD KDELCVVCGD KATGYHYRCI TCEGCKGFFR RTIQKNLHPT YSCKYEGKCV IDKVTRNQCQ ECRFKKCIFV GMATDLVLDD SKRLAKRKLI EENREKRRRE ELQKTIGHKP EPTDEEWELI KIVTEAHVAT NAQGSHWKQK RKFLPEDIGQ APIVNAPEGG KVDLEAFSQF TKIITPAITR VVDFAKKLPM FCELPCEDQI ILLKGCCMEI MSLRAAVRYD PESETLTLNG EMAVTRGQLK NGGLGVVSDA IFDLGMSLSS FNLDDTEVAL LQAVLLMSSD RPGLVCVERI EKCQEGFLLA FEHYINYRKH HVAHFWPKLL MKVTDLRMIG ACHASRFLHM KVECPTELFP PLFLEVFED
Expression Region 1-369
Protein Description Full length protein
Storage Buffer Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Still Have Questions? Leave a Message or Start an on-line Chat
Product Name Recombinant Chicken Thyroid hormone receptor beta(THRB),Mammalian cell
Code CSB-MP023514CH
Size Pls inquiry other sizes
Source Mammalian cell
Purity >85% (SDS-PAGE)
Tag Info The following tags are available.
N-terminal His-tagged and C-terminal Myc-tagged
N-terminal His-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Sequence MSGYIPSYLD KDELCVVCGD KATGYHYRCI TCEGCKGFFR RTIQKNLHPT YSCKYEGKCV IDKVTRNQCQ ECRFKKCIFV GMATDLVLDD SKRLAKRKLI EENREKRRRE ELQKTIGHKP EPTDEEWELI KIVTEAHVAT NAQGSHWKQK RKFLPEDIGQ APIVNAPEGG KVDLEAFSQF TKIITPAITR VVDFAKKLPM FCELPCEDQI ILLKGCCMEI MSLRAAVRYD PESETLTLNG EMAVTRGQLK NGGLGVVSDA IFDLGMSLSS FNLDDTEVAL LQAVLLMSSD RPGLVCVERI EKCQEGFLLA FEHYINYRKH HVAHFWPKLL MKVTDLRMIG ACHASRFLHM KVECPTELFP PLFLEVFED
Expression Region 1-369
Protein Description Full length protein
Storage Buffer Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Still Have Questions? Leave a Message or Start an on-line Chat

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