Recombinant Chicken Transcription factor SOX-2(SOX2)

Product Type Recombinant Protein
Uniprot No. P48430
Species Gallus gallus (Chicken)
Gene Names SOX2
Protein Names Recommended name: Transcription factor SOX-2 Short name= cSox2 Alternative name(s): delta EF2a
Storage Store at -20°C, for extended storage, conserve at -20°C or -80°C.
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Target Details This intronless gene encodes a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of this gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. Mutations in this gene have been associated with optic nerve hypoplasia and with syndromic microphthalmia, a severe form of structural eye malformation. This gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT).
HGNC 11195
RGD 1565646
MGI 98364
Function Transcriptional activator. May function as a switch in neuronal development. Downstream SRRT target that mediates the promotion of neural stem cell self-renewal (By similarity). Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation. In cooperation with other transcription factors, binds to the promoter sequence of the crystallin gene to activate transcription in the lens. Binds to the consensus DNA sequence 5'-TCATTGTTGTTG-3'.
Subcellular Location Nucleus
Tissue Specificity First expressed in the embryonic neural plate shortly before closure and expression continues in the neural tube. From stage 16 onwards, expressed throughout the CNS including the brain, with expression predominant in the undifferentiated cells of the neu
Database Links

KEGG: gga:396105

STRING: 9031.ENSGALP00000014363

UniGene: Gga.601

Pathway Hippo signaling pathway
Signaling pathways regulating pluripotency of stem cells

Product Details for Different Expression Systems

Product Name Recombinant Chicken Transcription factor SOX-2(SOX2),Yeast
Code CSB-YP022426CH
Size Pls inquiry other sizes
Source Yeast
Purity >85% (SDS-PAGE)
Tag Info The following tags are available.
N-terminal His-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Sequence MYNMMETELK PPAPQQTSGG GTGNSNSAAN NQKNSPDRVK RPMNAFMVWS RGQRRKMAQE NPKMHNSEIS KRLGAEWKLL SEAEKRPFID EAKRLRALHM KEHPDYKYRP RRKTKTLMKK DKYTLPGGLL APGTNTMTTG VGVGATLGAG VNQRMDSYAH MNGWTNGGYG MMQEQLGYPQ HPGLNAHNAA QMQPMHRYDV SALQYNSMTS SQTYMNGSPT YSMSYSQQGT PGMALGSMGS VVKTESSSSP PVVTSSSHSR APCQAGDLRD MISMYLPGAE VPEPAAPSRL HMSQHYQSAP VPGTAINGTL PLSHM
Expression Region 1-315
Protein Description Full length protein
Storage Buffer Tris-based buffer,50% glycerol
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Product Name Recombinant Chicken Transcription factor SOX-2(SOX2),E.coli
Code CSB-EP022426CH
Size Pls inquiry other sizes
Source E.coli
Purity >85% (SDS-PAGE)
Tag Info The following tags are available.
N-terminal His-tagged and C-terminal Myc-tagged
N-terminal His-SUMO-tagged and C-terminal Myc-tagged
N-terminal His-B2M-tagged and C-terminal Myc-tagged
N-terminal His-GST-tagged and C-terminal Myc-tagged
N-terminal His-tagged
N-terminal His-SUMO-tagged
N-terminal His-B2M-tagged
N-terminal His-GST-tagged
N-terminal GST-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Sequence MYNMMETELK PPAPQQTSGG GTGNSNSAAN NQKNSPDRVK RPMNAFMVWS RGQRRKMAQE NPKMHNSEIS KRLGAEWKLL SEAEKRPFID EAKRLRALHM KEHPDYKYRP RRKTKTLMKK DKYTLPGGLL APGTNTMTTG VGVGATLGAG VNQRMDSYAH MNGWTNGGYG MMQEQLGYPQ HPGLNAHNAA QMQPMHRYDV SALQYNSMTS SQTYMNGSPT YSMSYSQQGT PGMALGSMGS VVKTESSSSP PVVTSSSHSR APCQAGDLRD MISMYLPGAE VPEPAAPSRL HMSQHYQSAP VPGTAINGTL PLSHM
Expression Region 1-315
Protein Description Full length protein
Storage Buffer Tris-based buffer,50% glycerol
Still Have Questions? Leave a Message or Start an on-line Chat
Product Name Recombinant Chicken Transcription factor SOX-2(SOX2),Baculovirus
Code CSB-BP022426CH
Size Pls inquiry other sizes
Source Baculovirus
Purity >85% (SDS-PAGE)
Tag Info The following tags are available.
N-terminal His-tagged and C-terminal Myc-tagged
N-terminal His-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Sequence MYNMMETELK PPAPQQTSGG GTGNSNSAAN NQKNSPDRVK RPMNAFMVWS RGQRRKMAQE NPKMHNSEIS KRLGAEWKLL SEAEKRPFID EAKRLRALHM KEHPDYKYRP RRKTKTLMKK DKYTLPGGLL APGTNTMTTG VGVGATLGAG VNQRMDSYAH MNGWTNGGYG MMQEQLGYPQ HPGLNAHNAA QMQPMHRYDV SALQYNSMTS SQTYMNGSPT YSMSYSQQGT PGMALGSMGS VVKTESSSSP PVVTSSSHSR APCQAGDLRD MISMYLPGAE VPEPAAPSRL HMSQHYQSAP VPGTAINGTL PLSHM
Expression Region 1-315
Protein Description Full length protein
Storage Buffer Tris-based buffer,50% glycerol
Still Have Questions? Leave a Message or Start an on-line Chat
Product Name Recombinant Chicken Transcription factor SOX-2(SOX2),Mammalian cell
Code CSB-MP022426CH
Size Pls inquiry other sizes
Source Mammalian cell
Purity >85% (SDS-PAGE)
Tag Info The following tags are available.
N-terminal His-tagged and C-terminal Myc-tagged
N-terminal His-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Sequence MYNMMETELK PPAPQQTSGG GTGNSNSAAN NQKNSPDRVK RPMNAFMVWS RGQRRKMAQE NPKMHNSEIS KRLGAEWKLL SEAEKRPFID EAKRLRALHM KEHPDYKYRP RRKTKTLMKK DKYTLPGGLL APGTNTMTTG VGVGATLGAG VNQRMDSYAH MNGWTNGGYG MMQEQLGYPQ HPGLNAHNAA QMQPMHRYDV SALQYNSMTS SQTYMNGSPT YSMSYSQQGT PGMALGSMGS VVKTESSSSP PVVTSSSHSR APCQAGDLRD MISMYLPGAE VPEPAAPSRL HMSQHYQSAP VPGTAINGTL PLSHM
Expression Region 1-315
Protein Description Full length protein
Storage Buffer Tris-based buffer,50% glycerol
Still Have Questions? Leave a Message or Start an on-line Chat

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