Cyclin-dependent kinase 20
Cell cycle-related kinase
Cell division protein kinase 20
Store at -20°C, for extended storage, conserve at -20°C or -80°C.
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Involved in cell growth. Activates cdk2, a kinase involved in the control of the cell cycle, by phosphorylating residue 'Thr-160' (By similarity). Required for high-level Shh responses in the developing neural tube. Together with tbc1d32, controls the structure of the primary cilium by coordinating assembly of the ciliary membrane and axoneme, allowing gli2 to be properly activated in response to SHH signaling.
Nucleus, Cytoplasm, Cell projection, cilium
Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily