Recombinant Dictyostelium discoideum Histone H2A.x(H2AX)

Product Type Recombinant Protein
Uniprot No. Q54WG6
Abbreviation H2AX
Species Dictyostelium discoideum (Slime mold)
Gene Names H2AX
Protein Names Recommended name: Histone H2A.x
Storage The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Function Core component of nucleosome which plays a central role in DNA double strand break (DSB) repair. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling (By similarity). Phosphorylation of H2AX seems to be performed by atr1 and/or possibly dnapkcs, as ATM ortholog is absent in the genome of this organism.
Subcellular Location Nucleus, Chromosome
Protein Families Histone H2A family
Database Links

KEGG: ddi:DDB_G0279667

STRING: 44689.DDB0216271

Product Details for Different Expression Systems

Product Name Recombinant Dictyostelium discoideum Histone H2A.x(H2AX),Yeast
Code CSB-YP681774DKK
Size Pls inquiry other sizes
Source Yeast
Purity >85% (SDS-PAGE)
Tag Info The following tags are available.
N-terminal His-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Sequence MSETKPASSK PAAAAKPKKV IPRVSRTGEP KSKPESRSAR AGITFPVSRV DRLLREGRFA PRVESTAPVY LAAVLEYLVF EILELAHNTC SISKKTRITP QHINWAVGND LELNSLFQHV TIAYGGVLPT PQQSTGEKKK KPSKKAAEGS SQIY
Expression Region 1-154
Protein Description full length protein
Storage Buffer Tris-based buffer,50% glycerol
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Product Name Recombinant Dictyostelium discoideum Histone H2A.x(H2AX),E.coli
Code CSB-EP681774DKK
Size Pls inquiry other sizes
Source E.coli
Purity >85% (SDS-PAGE)
Tag Info The following tags are available.
N-terminal His-tagged and C-terminal Myc-tagged
N-terminal His-SUMO-tagged and C-terminal Myc-tagged
N-terminal His-B2M-tagged and C-terminal Myc-tagged
N-terminal His-GST-tagged and C-terminal Myc-tagged
N-terminal His-tagged
N-terminal His-SUMO-tagged
N-terminal His-B2M-tagged
N-terminal His-GST-tagged
N-terminal GST-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Sequence MSETKPASSK PAAAAKPKKV IPRVSRTGEP KSKPESRSAR AGITFPVSRV DRLLREGRFA PRVESTAPVY LAAVLEYLVF EILELAHNTC SISKKTRITP QHINWAVGND LELNSLFQHV TIAYGGVLPT PQQSTGEKKK KPSKKAAEGS SQIY
Expression Region 1-154
Protein Description full length protein
Storage Buffer Tris-based buffer,50% glycerol
Still Have Questions? Leave a Message or Start an on-line Chat
Product Name Recombinant Dictyostelium discoideum Histone H2A.x(H2AX),Baculovirus
Code CSB-BP681774DKK
Size Pls inquiry other sizes
Source Baculovirus
Purity >85% (SDS-PAGE)
Tag Info The following tags are available.
N-terminal His-tagged and C-terminal Myc-tagged
N-terminal His-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Sequence MSETKPASSK PAAAAKPKKV IPRVSRTGEP KSKPESRSAR AGITFPVSRV DRLLREGRFA PRVESTAPVY LAAVLEYLVF EILELAHNTC SISKKTRITP QHINWAVGND LELNSLFQHV TIAYGGVLPT PQQSTGEKKK KPSKKAAEGS SQIY
Expression Region 1-154
Protein Description full length protein
Storage Buffer Tris-based buffer,50% glycerol
Still Have Questions? Leave a Message or Start an on-line Chat
Product Name Recombinant Dictyostelium discoideum Histone H2A.x(H2AX),Mammalian cell
Code CSB-MP681774DKK
Size Pls inquiry other sizes
Source Mammalian cell
Purity >85% (SDS-PAGE)
Tag Info The following tags are available.
N-terminal His-tagged and C-terminal Myc-tagged
N-terminal His-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Sequence MSETKPASSK PAAAAKPKKV IPRVSRTGEP KSKPESRSAR AGITFPVSRV DRLLREGRFA PRVESTAPVY LAAVLEYLVF EILELAHNTC SISKKTRITP QHINWAVGND LELNSLFQHV TIAYGGVLPT PQQSTGEKKK KPSKKAAEGS SQIY
Expression Region 1-154
Protein Description full length protein
Storage Buffer Tris-based buffer,50% glycerol
Still Have Questions? Leave a Message or Start an on-line Chat

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