Recombinant Goat Interleukin-1 beta(IL1B)

Product Type Recombinant Protein
Uniprot No. P79162
Species Capra hircus (Goat)
Gene Names IL1B
Protein Names Recommended name: Interleukin-1 beta Short name= IL-1 beta
Storage Store at -20°C, for extended storage, conserve at -20°C or -80°C.
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Target Details This protein is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2.
HGNC 5992
RGD 2891
MGI 96543
Function Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B-cell activation and antibody production, and fibroblast proliferation and collagen production.
Subcellular Location Cytoplasm, cytosol, Lysosome, Secreted, exosome, Cytoplasmic vesicle, autophagosome, Secreted
Protein Families IL-1 family
Database Links

UniGene: Chi.15482

Pathway MAPK signaling pathway
Lipids and Inflammation in Atherogenesis
NF-kappa B signaling pathway
TNF signaling pathway
Necroptosis
Hematopoietic cell lineage
IL-17 signaling pathway
Inflammasome Signaling
NOD-like receptor signaling pathway
Osteoclast differentiation
Th17 cell differentiation
Toll-like receptor signaling pathway
AGE-RAGE signaling pathway in diabetic complications
Excitatory synapse pathway

Product Details for Different Expression Systems

Product Name Recombinant Goat Interleukin-1 beta(IL1B),Yeast
Code CSB-YP011614GO
Size Pls inquiry other sizes
Source Yeast
Purity >85% (SDS-PAGE)
Tag Info The following tags are available.
N-terminal His-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Sequence AAVQSVK CKLQDREQKS LVLDSPCVLK ALHLLSQEMS REVVFCMSFV QGEERDNKIP VALGIRDKNL YLSWVKKGDT PTLQLEEVDP KVYPKRNMEK RFVFYKTEIK NTVEFESVLY PNWYISTSQI EEKPVFLGHF RGGQDITDFR METLSP
Expression Region 114-266
Protein Description Full Length of Mature Protein
Storage Buffer Tris-based buffer,50% glycerol
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Product Name Recombinant Goat Interleukin-1 beta(IL1B),E.coli
Code CSB-EP011614GO
Size Pls inquiry other sizes
Source E.coli
Purity >85% (SDS-PAGE)
Tag Info The following tags are available.
N-terminal His-tagged and C-terminal Myc-tagged
N-terminal His-SUMO-tagged and C-terminal Myc-tagged
N-terminal His-B2M-tagged and C-terminal Myc-tagged
N-terminal His-GST-tagged and C-terminal Myc-tagged
N-terminal His-tagged
N-terminal His-SUMO-tagged
N-terminal His-B2M-tagged
N-terminal His-GST-tagged
N-terminal GST-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Sequence AAVQSVK CKLQDREQKS LVLDSPCVLK ALHLLSQEMS REVVFCMSFV QGEERDNKIP VALGIRDKNL YLSWVKKGDT PTLQLEEVDP KVYPKRNMEK RFVFYKTEIK NTVEFESVLY PNWYISTSQI EEKPVFLGHF RGGQDITDFR METLSP
Expression Region 114-266
Protein Description Full Length of Mature Protein
Storage Buffer Tris-based buffer,50% glycerol
Still Have Questions? Leave a Message or Start an on-line Chat
Product Name Recombinant Goat Interleukin-1 beta(IL1B),Baculovirus
Code CSB-BP011614GO
Size Pls inquiry other sizes
Source Baculovirus
Purity >85% (SDS-PAGE)
Tag Info The following tags are available.
N-terminal His-tagged and C-terminal Myc-tagged
N-terminal His-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Sequence AAVQSVK CKLQDREQKS LVLDSPCVLK ALHLLSQEMS REVVFCMSFV QGEERDNKIP VALGIRDKNL YLSWVKKGDT PTLQLEEVDP KVYPKRNMEK RFVFYKTEIK NTVEFESVLY PNWYISTSQI EEKPVFLGHF RGGQDITDFR METLSP
Expression Region 114-266
Protein Description Full Length of Mature Protein
Storage Buffer Tris-based buffer,50% glycerol
Still Have Questions? Leave a Message or Start an on-line Chat
Product Name Recombinant Goat Interleukin-1 beta(IL1B),Mammalian cell
Code CSB-MP011614GO
Size Pls inquiry other sizes
Source Mammalian cell
Purity >85% (SDS-PAGE)
Tag Info The following tags are available.
N-terminal His-tagged and C-terminal Myc-tagged
N-terminal His-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Sequence AAVQSVK CKLQDREQKS LVLDSPCVLK ALHLLSQEMS REVVFCMSFV QGEERDNKIP VALGIRDKNL YLSWVKKGDT PTLQLEEVDP KVYPKRNMEK RFVFYKTEIK NTVEFESVLY PNWYISTSQI EEKPVFLGHF RGGQDITDFR METLSP
Expression Region 114-266
Protein Description Full Length of Mature Protein
Storage Buffer Tris-based buffer,50% glycerol
Still Have Questions? Leave a Message or Start an on-line Chat

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