Recombinant Guinea pig Rho GDP-dissociation inhibitor 1(ARHGDIA)

Product Type Recombinant Protein
Uniprot No. P80237
Species Cavia porcellus (Guinea pig)
Gene Names ARHGDIA
Protein Names Recommended name: Rho GDP-dissociation inhibitor 1 Short name= Rho GDI 1 Alternative name(s): Rho-GDI alpha
Storage Store at -20°C, for extended storage, conserve at -20°C or -80°C.
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
HGNC 678
RGD 1359547
MGI 2178103
Function Controls Rho proteins homeostasis. Regulates the GDP/GTP exchange reaction of the Rho proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them. Retains Rho proteins such as CDC42, RAC1 and RHOA in an inactive cytosolic pool, regulating their stability and protecting them from degradation. Actively involved in the recycling and distribution of activated Rho GTPases in the cell, mediates extraction from membranes of both inactive and activated molecules due its exceptionally high affinity for prenylated forms. Through the modulation of Rho proteins, may play a role in cell motility regulation. In glioma cells, inhibits cell migration and invasion by mediating the signals of SEMA5A and PLXNB3 that lead to inactivation of RAC1 (By similarity).
Subcellular Location Cytoplasm
Protein Families Rho GDI family
Pathway Inhibitors of axonal regeneration
Neurotrophin signaling pathway

Product Details for Different Expression Systems

Product Name Recombinant Guinea pig Rho GDP-dissociation inhibitor 1(ARHGDIA),Yeast
Code CSB-YP002037GU
Size Pls inquiry other sizes
Source Yeast
Purity >85% (SDS-PAGE)
Tag Info The following tags are available.
N-terminal His-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Sequence VAVSADPNEP NVIVTRLTLV CSTAPGPLEL DLTGDLESFK IKISFRYIQH TYRKGVKIDK TDYMVGSYGP RAEEYEFLTP MEEAPKGMLA RFTDDDKTDH LSGERNLTIK K
Expression Region 1-111
Protein Description Full length protein
Storage Buffer Tris-based buffer,50% glycerol
Still Have Questions? Leave a Message or Start an on-line Chat
Product Name Recombinant Guinea pig Rho GDP-dissociation inhibitor 1(ARHGDIA),E.coli
Code CSB-EP002037GU
Size Pls inquiry other sizes
Source E.coli
Purity >85% (SDS-PAGE)
Tag Info The following tags are available.
N-terminal His-tagged and C-terminal Myc-tagged
N-terminal His-SUMO-tagged and C-terminal Myc-tagged
N-terminal His-B2M-tagged and C-terminal Myc-tagged
N-terminal His-GST-tagged and C-terminal Myc-tagged
N-terminal His-tagged
N-terminal His-SUMO-tagged
N-terminal His-B2M-tagged
N-terminal His-GST-tagged
N-terminal GST-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Sequence VAVSADPNEP NVIVTRLTLV CSTAPGPLEL DLTGDLESFK IKISFRYIQH TYRKGVKIDK TDYMVGSYGP RAEEYEFLTP MEEAPKGMLA RFTDDDKTDH LSGERNLTIK K
Expression Region 1-111
Protein Description Full length protein
Storage Buffer Tris-based buffer,50% glycerol
Still Have Questions? Leave a Message or Start an on-line Chat
Product Name Recombinant Guinea pig Rho GDP-dissociation inhibitor 1(ARHGDIA),Baculovirus
Code CSB-BP002037GU
Size Pls inquiry other sizes
Source Baculovirus
Purity >85% (SDS-PAGE)
Tag Info The following tags are available.
N-terminal His-tagged and C-terminal Myc-tagged
N-terminal His-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Sequence VAVSADPNEP NVIVTRLTLV CSTAPGPLEL DLTGDLESFK IKISFRYIQH TYRKGVKIDK TDYMVGSYGP RAEEYEFLTP MEEAPKGMLA RFTDDDKTDH LSGERNLTIK K
Expression Region 1-111
Protein Description Full length protein
Storage Buffer Tris-based buffer,50% glycerol
Still Have Questions? Leave a Message or Start an on-line Chat
Product Name Recombinant Guinea pig Rho GDP-dissociation inhibitor 1(ARHGDIA),Mammalian cell
Code CSB-MP002037GU
Size Pls inquiry other sizes
Source Mammalian cell
Purity >85% (SDS-PAGE)
Tag Info The following tags are available.
N-terminal His-tagged and C-terminal Myc-tagged
N-terminal His-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Sequence VAVSADPNEP NVIVTRLTLV CSTAPGPLEL DLTGDLESFK IKISFRYIQH TYRKGVKIDK TDYMVGSYGP RAEEYEFLTP MEEAPKGMLA RFTDDDKTDH LSGERNLTIK K
Expression Region 1-111
Protein Description Full length protein
Storage Buffer Tris-based buffer,50% glycerol
Still Have Questions? Leave a Message or Start an on-line Chat

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