Recombinant Horse Insulin-like growth factor II(IGF2)

Product Type Recombinant Protein
Uniprot No. P51459
Species Equus caballus (Horse)
Gene Names IGF2
Protein Names Recommended name: Insulin-like growth factor II Short name= IGF-II Alternative name(s): Somatomedin-A Cleaved into the following 2 chains: 1. Insulin-like growth factor II 2. Preptin
Storage Store at -20°C, for extended storage, conserve at -20°C or -80°C.
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Target Details This gene encodes a member of the insulin family of polypeptide growth factors that is involved in development and growth. It is an imprinted gene and is expressed only from the paternally inherited allele. It is a candidate gene for eating disorders. There is a read-through, INS-IGF2, which aligns to this gene at the 3 region and to the upstream INS gene at the 5 region. Alternatively spliced transcript variants, encoding either the same or different isoform, have been found for this gene.
HGNC 5466
RGD 2870
MGI 96434
Function The insulin-like growth factors possess growth-promoting activity. Major fetal growth hormone in mammals. Plays a key role in regulating fetoplacental development. IGF-II is influenced by placental lactogen. Also involved in tissue differentiation. Positively regulates myogenic transcription factor MYOD1 function by facilitating the recruitment of transcriptional coactivators, thereby controlling muscle terminal differentiation. In adults, involved in glucose metabolism in adipose tissue, skeletal muscle and liver.
Subcellular Location Secreted
Protein Families Insulin family
Database Links

KEGG: ecb:100034182

UniGene: Eca.13091

Pathway MAPK signaling pathway
PI3K-Akt signaling pathway
Ras signaling pathway

Product Details for Different Expression Systems

Product Name Recombinant Horse Insulin-like growth factor II(IGF2),Yeast
Code CSB-YP011088HO
Size Pls inquiry other sizes
Source Yeast
Purity >85% (SDS-PAGE)
Tag Info The following tags are available.
N-terminal His-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Sequence AYRPSE TLCGGELVDT LQFVCGDRGF YFSRPASRIN RRSRGIVEEC CFRSCDLALL ETYCATPAKS E
Expression Region 25-91
Protein Description Full Length of Mature Protein
Storage Buffer Tris-based buffer,50% glycerol
Still Have Questions? Leave a Message or Start an on-line Chat
Product Name Recombinant Horse Insulin-like growth factor II(IGF2),E.coli
Code CSB-EP011088HO
Size Pls inquiry other sizes
Source E.coli
Purity >85% (SDS-PAGE)
Tag Info The following tags are available.
N-terminal His-tagged and C-terminal Myc-tagged
N-terminal His-SUMO-tagged and C-terminal Myc-tagged
N-terminal His-B2M-tagged and C-terminal Myc-tagged
N-terminal His-GST-tagged and C-terminal Myc-tagged
N-terminal His-tagged
N-terminal His-SUMO-tagged
N-terminal His-B2M-tagged
N-terminal His-GST-tagged
N-terminal GST-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Sequence AYRPSE TLCGGELVDT LQFVCGDRGF YFSRPASRIN RRSRGIVEEC CFRSCDLALL ETYCATPAKS E
Expression Region 25-91
Protein Description Full Length of Mature Protein
Storage Buffer Tris-based buffer,50% glycerol
Still Have Questions? Leave a Message or Start an on-line Chat
Product Name Recombinant Horse Insulin-like growth factor II(IGF2),Baculovirus
Code CSB-BP011088HO
Size Pls inquiry other sizes
Source Baculovirus
Purity >85% (SDS-PAGE)
Tag Info The following tags are available.
N-terminal His-tagged and C-terminal Myc-tagged
N-terminal His-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Sequence AYRPSE TLCGGELVDT LQFVCGDRGF YFSRPASRIN RRSRGIVEEC CFRSCDLALL ETYCATPAKS E
Expression Region 25-91
Protein Description Full Length of Mature Protein
Storage Buffer Tris-based buffer,50% glycerol
Still Have Questions? Leave a Message or Start an on-line Chat
Product Name Recombinant Horse Insulin-like growth factor II(IGF2),Mammalian cell
Code CSB-MP011088HO
Size Pls inquiry other sizes
Source Mammalian cell
Purity >85% (SDS-PAGE)
Tag Info The following tags are available.
N-terminal His-tagged and C-terminal Myc-tagged
N-terminal His-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Sequence AYRPSE TLCGGELVDT LQFVCGDRGF YFSRPASRIN RRSRGIVEEC CFRSCDLALL ETYCATPAKS E
Expression Region 25-91
Protein Description Full Length of Mature Protein
Storage Buffer Tris-based buffer,50% glycerol
Still Have Questions? Leave a Message or Start an on-line Chat

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