Recombinant Human SKI family transcriptional corepressor 1 (SKOR1), partial

Code CSB-YP308064HU
MSDS
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Source Yeast
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Code CSB-EP308064HU
MSDS
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Source E.coli
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Code CSB-EP308064HU-B
MSDS
Size Pls inquire
Source E.coli
Conjugate Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code CSB-BP308064HU
MSDS
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Source Baculovirus
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Code CSB-MP308064HU
MSDS
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Source Mammalian cell
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Product Details

Purity
>85% (SDS-PAGE)
Target Names
SKOR1
Uniprot No.
Alternative Names
SKOR1; CORL1; FUSSEL15; LBXCOR1; SKI family transcriptional corepressor 1; Functional Smad-suppressing element on chromosome 15; Fussel-15; LBX1 corepressor 1; Ladybird homeobox corepressor 1
Species
Homo sapiens (Human)
Protein Length
Partial
Tag Info
Tag type will be determined during the manufacturing process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form
Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization
Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet
Please contact us to get it.

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Target Background

Function
Acts as a transcriptional corepressor of LBX1. Inhibits BMP signaling.
Gene References into Functions
  1. Permanent expression of Fussel-15 in keloid and skin sclerosis fibroblasts could be involved in the pathogenesis of these conditions. PMID: 21641385
  2. a novel gene, fussel-15 (functional smad suppressing element on chromosome 15) with high homology to the recently discovered Fussel-18 protein. PMID: 17292623
  3. MEIS1 and LBXCOR1 are developmental factors and raise new pathophysiologic questions for RLS. PMID: 18541116
  4. Observational study of gene-disease association. (HuGE Navigator) PMID: 19822783
  5. Observational study of gene-disease association. (HuGE Navigator) PMID: 19279021
  6. Observational study and genome-wide association study of gene-disease association. (HuGE Navigator) PMID: 17637780

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Subcellular Location
Nucleus.
Protein Families
SKI family
Tissue Specificity
Present specifically in cerebellar Purkinje cells (at protein level).
Database Links

HGNC: 21326

OMIM: 611273

KEGG: hsa:390598

STRING: 9606.ENSP00000369374

UniGene: Hs.451224

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