Recombinant Human Transcription factor TFIIIB component B' homolog (BDP1), partial

Code CSB-YP406639HU
MSDS
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Source Yeast
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Code CSB-EP406639HU
MSDS
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Source E.coli
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Code CSB-EP406639HU-B
MSDS
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Source E.coli
Conjugate Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code CSB-BP406639HU
MSDS
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Source Baculovirus
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Code CSB-MP406639HU
MSDS
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Source Mammalian cell
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Product Details

Purity
>85% (SDS-PAGE)
Target Names
BDP1
Uniprot No.
Alternative Names
BDP1; KIAA1241; KIAA1689; TFNRTranscription factor TFIIIB component B'' homolog; Transcription factor IIIB 150; TFIIIB150; Transcription factor-like nuclear regulator
Species
Homo sapiens (Human)
Protein Length
Partial
Tag Info
Tag type will be determined during the manufacturing process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form
Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization
Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet
Please contact us to get it.

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Target Background

Function
General activator of RNA polymerase III transcription. Requires for transcription from all three types of polymerase III promoters. Requires for transcription of genes with internal promoter elements and with promoter elements upstream of the initiation site.
Gene References into Functions
  1. Linkage study and exome sequencing identify a BDP1 mutation associated with hereditary hearing loss. PMID: 24312468
  2. Human BDP1 protein represents essential components of TFIIIC1 and TFIIIC1-like activities. PMID: 15096501
  3. Maf1 occupancy of Pol III genes is inversely correlated with that of the initiation factor TFIIIB (subunit Bdp1) and Pol III PMID: 17499043
  4. PTEN represses RNA polymerase III-dependent transcription by targeting the TFIIIB complex PMID: 18391023
Subcellular Location
Nucleus.
Tissue Specificity
Isoform 2 is highly expressed in cerebellum.
Database Links

HGNC: 13652

OMIM: 607012

KEGG: hsa:55814

STRING: 9606.ENSP00000351575

UniGene: Hs.258272

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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