Recombinant Human 28S ribosomal protein S22, mitochondrial (MRPS22)

Code CSB-YP014908HU
MSDS
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Source Yeast
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Code CSB-EP014908HU-B
MSDS
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Source E.coli
Conjugate Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code CSB-BP014908HU
MSDS
Size Pls inquire
Source Baculovirus
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Code CSB-MP014908HU
MSDS
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Source Mammalian cell
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Product Details

Purity
>85% (SDS-PAGE)
Target Names
MRPS22
Uniprot No.
Alternative Names
28S ribosomal protein S22; C3orf5; COXPD5; GIBT; GK002; mitochondrial; Mitochondrial ribosomal protein S22; MRP-S22; MRPS22; RPM S22; RPMS22; RT22_HUMAN; S22mt
Species
Homo sapiens (Human)
Expression Region
1-360
Target Protein Sequence
MAPLGTTVLL WSLLRSSPGV ERVCFRARIQ PWHGGLLQPL PCSFEMGLPR RRFSSEAAES GSPETKKPTF MDEEVQSILT KMTGLNLQKT FKPAIQELKP PTYKLMTQAQ LEEATRQAVE AAKVRLKMPP VLEERVPIND VLAEDKILEG TETTKYVFTD ISYSIPHRER FIVVREPSGT LRKASWEERD RMIQVYFPKE GRKILTPIIF KEENLRTMYS QDRHVDVLNL CFAQFEPDST EYIKVHHKTY EDIDKRGKYD LLRSTRYFGG MVWYFVNNKK IDGLLIDQIQ RDLIDDATNL VQLYHVLHPD GQSAQGAKDQ AAEGINLIKV FAKTEAQKGA YIELTLQTYQ EALSRHSAAS
Protein Length
Full length protein
Tag Info
Tag type will be determined during the manufacturing process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form
Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization
Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet
Please contact us to get it.

Customer Reviews and Q&A

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Target Background

Gene References into Functions
  1. hypertrophic cardiomyopathy and tubulopathy may not be considered as constant features of MRPS22 PMID: 28752220
  2. A mutation in the MRPS22 gene led to reduction of 12sRNA in fibroblasts and fatal neonatal hypertrophic cardiomyopathy & kidney tubulopathy. PMID: 17873122
  3. The effect of mutated MRPS22 on the assembly of the small and large ribosomal subunits in human mitochondria is reported. PMID: 18539099
Involvement in disease
Combined oxidative phosphorylation deficiency 5 (COXPD5)
Subcellular Location
Mitochondrion.
Protein Families
Mitochondrion-specific ribosomal protein mS22 family
Database Links

HGNC: 14508

OMIM: 605810

KEGG: hsa:56945

STRING: 9606.ENSP00000310785

UniGene: Hs.745001

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