Recombinant Human 60S ribosomal protein L7a (RPL7A)

Code CSB-YP020303HU
MSDS
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Source Yeast
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Code CSB-EP020303HU
MSDS
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Source E.coli
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Code CSB-EP020303HU-B
MSDS
Size Pls inquire
Source E.coli
Conjugate Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code CSB-BP020303HU
MSDS
Size Pls inquire
Source Baculovirus
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Code CSB-MP020303HU
MSDS
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Source Mammalian cell
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Product Details

Purity
>85% (SDS-PAGE)
Target Names
RPL7A
Uniprot No.
Alternative Names
60S ribosomal protein L7a; L7A; MGC103146; PLA X polypeptide ; PLA-X polypeptide; ribosomal protein L7a; RL7A_HUMAN; RP23-414L19.4; RPL7A; SURF 3; SURF-3; SURF3 ; surfeit 3; Surfeit locus protein 3; Thyroid hormone receptor uncoupling protein; TRUP
Species
Homo sapiens (Human)
Expression Region
2-266
Target Protein Sequence
PKGKKAKGK KVAPAPAVVK KQEAKKVVNP LFEKRPKNFG IGQDIQPKRD LTRFVKWPRY IRLQRQRAIL YKRLKVPPAI NQFTQALDRQ TATQLLKLAH KYRPETKQEK KQRLLARAEK KAAGKGDVPT KRPPVLRAGV NTVTTLVENK KAQLVVIAHD VDPIELVVFL PALCRKMGVP YCIIKGKARL GRLVHRKTCT TVAFTQVNSE DKGALAKLVE AIRTNYNDRY DEIRRHWGGN VLGPKSVARI AKLEKAKAKE LATKLG
Protein Length
Full Length of Mature Protein
Tag Info
Tag type will be determined during the manufacturing process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form
Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization
Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet
Please contact us to get it.

Customer Reviews and Q&A

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Target Background

Gene References into Functions
  1. X-ray diffraction data of RPL7a were collected to a resolution of 3.5 A from a crystal belonging to the tetragonal space group P4(1)22 or P4(3)22 with unit-cell parameters a = 92.28, b = 92.28, c = 236.59 A PMID: 21505254
  2. ethanol-induced alteration in expression may mediate the promoting effects of ethanol on breast cancer development PMID: 11759826
  3. the L7a protein contains two RNA-binding domains: one encompassing aa 52-100 (RNAB1) and the other encompassing aa 101-161 (RNAB2) PMID: 15361074
  4. Under-expression of RPL7A may be involved in the carcinogenesis of osteosarcoma PMID: 19125294
Involvement in disease
Chromosomal recombination involving RPL7A activates the receptor kinase domain of the TRK oncogene.
Protein Families
Eukaryotic ribosomal protein eL8 family
Database Links

HGNC: 10364

OMIM: 185640

KEGG: hsa:6130

STRING: 9606.ENSP00000361076

UniGene: Hs.499839

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