Recombinant Human BUD13 homolog (BUD13)

Code CSB-YP863104HU
MSDS
Size Pls inquire
Source Yeast
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Code CSB-EP863104HU
MSDS
Size Pls inquire
Source E.coli
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Code CSB-EP863104HU-B
MSDS
Size Pls inquire
Source E.coli
Conjugate Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code CSB-BP863104HU
MSDS
Size Pls inquire
Source Baculovirus
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Code CSB-MP863104HU
MSDS
Size Pls inquire
Source Mammalian cell
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Product Details

Purity
>85% (SDS-PAGE)
Target Names
BUD13
Uniprot No.
Alternative Names
Bud13; BUD13 homolog (S. cerevisiae); BUD13 homolog; BUD13_HUMAN; Cwc26; FLJ27090; fSAP71; Functional spliceosome-associated protein 71; MGC13125; OTTHUMP00000042639; OTTHUMP00000042640
Species
Homo sapiens (Human)
Expression Region
1-619
Target Protein Sequence
MAAAPPLSKA EYLKRYLSGA DAGVDRGSES GRKRRKKRPK PGGAGGKGMR IVDDDVSWTA ISTTKLEKEE EEDDGDLPVV AEFVDERPEE VKQMEAFRSS AKWKLLGGHN EDLPSNRHFR HDTPDSSPRR VRHGTPDPSP RKDRHDTPDP SPRRARHDTP DPSPLRGARH DSDTSPPRRI RHDSSDTSPP RRARHDSPDP SPPRRPQHNS SGASPRRVRH DSPDPSPPRR ARHGSSDISS PRRVHNNSPD TSRRTLGSSD TQQLRRARHD SPDLAPNVTY SLPRTKSGKA PERASSKTSP HWKESGASHL SFPKNSKYEY DPDISPPRKK QAKSHFGDKK QLDSKGDCQK ATDSDLSSPR HKQSPGHQDS DSDLSPPRNR PRHRSSDSDL SPPRRRQRTK SSDSDLSPPR RSQPPGKKAA HMYSGAKTGL VLTDIQREQQ ELKEQDQETM AFEAEFQYAE TVFRDKSGRK RNLKLERLEQ RRKAEKDSER DELYAQWGKG LAQSRQQQQN VEDAMKEMQK PLARYIDDED LDRMLREQER EGDPMANFIK KNKAKENKNK KVRPRYSGPA PPPNRFNIWP GYRWDGVDRS NGFEQKRFAR LASKKAVEEL AYKWSVEDM
Protein Length
full length protein
Tag Info
Tag type will be determined during the manufacturing process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form
Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization
Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet
Please contact us to get it.

Customer Reviews and Q&A

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Target Background

Function
Involved in pre-mRNA splicing as component of the activated spliceosome.
Gene References into Functions
  1. Data concluded that novel mutations in BUD13 did not confer risk for MetS in our study population, but these mutations changed the level of metabolic complements. PMID: 28659142
  2. by an integrated analysis of the genotypes and the serum levels of APOA5, BUD13 and triglyceride, we observed that BUD13 was another potential mediator, besides APOA5, of the association between rs651821 and serum triglyceride. rs671 (ALDH2), an east Asian-specific common variant, was found to be associated with MetS (Pcombined = 9.7 x 10(-22) ) in Han Chinese PMID: 28371326
  3. When the inter-dependence between alleles was examined using conditional models, five loci on BUD13, ZNF259, and ApoA5 showed possible independent associations. PMID: 26634697
  4. Single nucleotide polymorphisms (Rs17119975) of BUD13 protein did not increase the risk of CHD in the Chinese population. PMID: 26397108
  5. Common SNPs within the BUD13-APOA5 gene region can effect triglyceride and LDL cholesterol response to statin therapy. PMID: 25900265
  6. Single nucleotide polymorphism bud13 gene is associated with hyperlipidaemia. PMID: 24780069
  7. Significant linkage disequilibria were noted among ZNF259, BUD13 and MLXIPL SNPs and serum lipid levels. PMID: 24989072

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Subcellular Location
Nucleus.
Protein Families
CWC26 family
Database Links

HGNC: 28199

KEGG: hsa:84811

STRING: 9606.ENSP00000260210

UniGene: Hs.437341

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