||Homo sapiens (Human)
Chromobox protein homolog 1
Heterochromatin protein 1 homolog beta
Short name= HP1 beta
Heterochromatin protein p25
Modifier 1 protein
||Store at -20°C, for extended storage, conserve at -20°C or -80°C.
||Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
||This gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family . The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The protein may play an important role in the epigenetic control of chromatin structure and gene expression. Several related pseudogenes are located on chromosomes 1, 3, and X. Multiple alternatively spliced variants, encoding the same protein, have been identified.