Recombinant Human Indoleamine 2,3-dioxygenase 2(IDO2),partial

Code CSB-YP010997HU
Product Type Recombinant Protein
Size US$2010
Uniprot No. Q6ZQW0
Abbreviation IDO2
Relevance Catalyzes the first and rate-limiting step in the kynurenine pathway of tryptophan catabolism.
Image
  • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Storage Buffer Tris-based buffer,50% glycerol
Alias Indoleamine 2,3-dioxygenase-like protein 1Indoleamine-pyrrole 2,3-dioxygenase-like protein 1
Species Homo sapiens (Human)
Purity Greater than 90% as determined by SDS-PAGE.
Sequence MEPHRPNVKTAVPLSLESYHISEEYGFLLPDSLKELPDHYRPWMEIANKLPQLIDAHQLQAHVDKMPLLSCQFLKGHREQRLAHLVLSFLTMGYVWQEGEAQPAEVLPRNLALPFVEVSRNLGLPPILVHSDLVLTNWTKKDPDGFLEIGNLETIISFPGGESLHGFILVTALVEKEAVPGIKALVQATNAILQPNQEALLQALQRLRLSIQDITKTLGQMHDYVDPDIFYAGIRIFLSGWKDNPAMPAGLMYEGVSQEPLKYSGGSAAQSTVLHAFDEFLGIRHSKESGDFLYRMRDYMPPSHKAFIEDIHSAPSLRDYILSSGQDHLLTAYNQCVQALAELRSYHITMVTKYLITAAAKAKHGKPNHLPGPPQALKDRGTGGTAVMSFLKSVRDKTLESILHPRG
Source Yeast
Gene Names IDO2
Protein Names Recommended name: Indoleamine 2,3-dioxygenase 2 Short name= IDO-2 EC= 1.13.11.-Alternative name(s): Indoleamine 2,3-dioxygenase-like protein 1 Indoleamine-pyrrole 2,3-dioxygenase-like protein 1
Expression Region 14-420aa
Tag Info N-terminal 6xHis-tagged
Mol. Weight 50.4kDa
Protein Description Partial
Storage The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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Function Catalyzes the first and rate limiting step of the catabolism of the essential amino acid tryptophan along the kynurenine pathway
Protein Families Indoleamine 2,3-dioxygenase family
Tissue Specificity Detected in liver, small intestine, spleen, placenta, thymus, lung, brain, kidney, and colon (PubMed:17671174). Also expressed at low level in testis and thyroid. Not expressed in the majority of human tumor samples (>99%) (PubMed:25691885).
Database Links

HGNC: 27269

OMIM: 612129

KEGG: hsa:169355

STRING: 9606.ENSP00000443432

UniGene: Hs.676257

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