Recombinant Human Iroquois-class homeodomain protein IRX-5(IRX5)

Product Type Recombinant Protein
Uniprot No. P78411
Species Homo sapiens (Human)
Gene Names IRX5
Protein Names Recommended name: Iroquois-class homeodomain protein IRX-5 Alternative name(s): Homeodomain protein IRX-2A Homeodomain protein IRXB2 Iroquois homeobox protein 5
Storage Store at -20°C, for extended storage, conserve at -20°C or -80°C.
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
HGNC 14361
RGD 1565518
MGI 1859086
Function Establishes the cardiac repolarization gradient by its repressive actions on the KCND2 potassium-channel gene. Required for retinal cone bipolar cell differentiation. May regulate contrast adaptation in the retina and control specific aspects of visual function in circuits of the mammalian retina (By similarity). Could be involved in the regulation of both the cell cycle and apoptosis in prostate cancer cells. Involved in craniofacial and gonadal development. Modulates the migration of progenitor cell populations in branchial arches and gonads by repressing CXCL12.
Involvement in disease Hamamy syndrome (HMMS)
Subcellular Location Nucleus
Protein Families TALE/IRO homeobox family
Database Links

HGNC: 14361

OMIM: 606195

KEGG: hsa:10265

STRING: 9606.ENSP00000378132

UniGene: Hs.435730

Product Details for Different Expression Systems

Product Name Recombinant Human Iroquois-class homeodomain protein IRX-5(IRX5),Yeast
Code CSB-YP011837HU
Size Pls inquiry other sizes
Source Yeast
Purity >85% (SDS-PAGE)
Tag Info The following tags are available.
N-terminal His-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Sequence MSYPQGYLYQ PSASLALYSC PAYSTSVISG PRTDELGRSS SGSAFSPYAG STAFTAPSPG YNSHLQYGAD PAAAAAAAFS SYVGSPYDHT PGMAGSLGYH PYAAPLGSYP YGDPAYRKNA TRDATATLKA WLNEHRKNPY PTKGEKIMLA IITKMTLTQV STWFANARRR LKKENKMTWT PRNRSEDEEE EENIDLEKND EDEPQKPEDK GDPEGPEAGG AEQKAASGCE RLQGPPTPAG KETEGSLSDS DFKEPPSEGR LDALQGPPRT GGPSPAGPAA ARLAEDPAPH YPAGAPAPGP HPAAGEVPPG PGGPSVIHSP PPPPPPAVLA KPKLWSLAEI ATSSDKVKDG GGGNEGSPCP PCPGPIAGQA LGGSRASPAP APSRSPSAQC PFPGGTVLSR PLYYTAPFYP GYTNYGSFGH LHGHPGPGPG PTTGPGSHFN GLNQTVLNRA DALAKDPKML RSQSQLDLCK DSPYELKKGM SDI
Expression Region 1-483
Protein Description Full length protein
Storage Buffer Tris-based buffer,50% glycerol
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Product Name Recombinant Human Iroquois-class homeodomain protein IRX-5(IRX5),E.coli
Code CSB-EP011837HU
Size Pls inquiry other sizes
Source E.coli
Purity >85% (SDS-PAGE)
Tag Info The following tags are available.
N-terminal His-tagged and C-terminal Myc-tagged
N-terminal His-SUMO-tagged and C-terminal Myc-tagged
N-terminal His-B2M-tagged and C-terminal Myc-tagged
N-terminal His-GST-tagged and C-terminal Myc-tagged
N-terminal His-tagged
N-terminal His-SUMO-tagged
N-terminal His-B2M-tagged
N-terminal His-GST-tagged
N-terminal GST-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Sequence MSYPQGYLYQ PSASLALYSC PAYSTSVISG PRTDELGRSS SGSAFSPYAG STAFTAPSPG YNSHLQYGAD PAAAAAAAFS SYVGSPYDHT PGMAGSLGYH PYAAPLGSYP YGDPAYRKNA TRDATATLKA WLNEHRKNPY PTKGEKIMLA IITKMTLTQV STWFANARRR LKKENKMTWT PRNRSEDEEE EENIDLEKND EDEPQKPEDK GDPEGPEAGG AEQKAASGCE RLQGPPTPAG KETEGSLSDS DFKEPPSEGR LDALQGPPRT GGPSPAGPAA ARLAEDPAPH YPAGAPAPGP HPAAGEVPPG PGGPSVIHSP PPPPPPAVLA KPKLWSLAEI ATSSDKVKDG GGGNEGSPCP PCPGPIAGQA LGGSRASPAP APSRSPSAQC PFPGGTVLSR PLYYTAPFYP GYTNYGSFGH LHGHPGPGPG PTTGPGSHFN GLNQTVLNRA DALAKDPKML RSQSQLDLCK DSPYELKKGM SDI
Expression Region 1-483
Protein Description Full length protein
Storage Buffer Tris-based buffer,50% glycerol
Still Have Questions? Leave a Message or Start an on-line Chat
Product Name Recombinant Human Iroquois-class homeodomain protein IRX-5(IRX5),Baculovirus
Code CSB-BP011837HU
Size Pls inquiry other sizes
Source Baculovirus
Purity >85% (SDS-PAGE)
Tag Info The following tags are available.
N-terminal His-tagged and C-terminal Myc-tagged
N-terminal His-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Sequence MSYPQGYLYQ PSASLALYSC PAYSTSVISG PRTDELGRSS SGSAFSPYAG STAFTAPSPG YNSHLQYGAD PAAAAAAAFS SYVGSPYDHT PGMAGSLGYH PYAAPLGSYP YGDPAYRKNA TRDATATLKA WLNEHRKNPY PTKGEKIMLA IITKMTLTQV STWFANARRR LKKENKMTWT PRNRSEDEEE EENIDLEKND EDEPQKPEDK GDPEGPEAGG AEQKAASGCE RLQGPPTPAG KETEGSLSDS DFKEPPSEGR LDALQGPPRT GGPSPAGPAA ARLAEDPAPH YPAGAPAPGP HPAAGEVPPG PGGPSVIHSP PPPPPPAVLA KPKLWSLAEI ATSSDKVKDG GGGNEGSPCP PCPGPIAGQA LGGSRASPAP APSRSPSAQC PFPGGTVLSR PLYYTAPFYP GYTNYGSFGH LHGHPGPGPG PTTGPGSHFN GLNQTVLNRA DALAKDPKML RSQSQLDLCK DSPYELKKGM SDI
Expression Region 1-483
Protein Description Full length protein
Storage Buffer Tris-based buffer,50% glycerol
Still Have Questions? Leave a Message or Start an on-line Chat
Product Name Recombinant Human Iroquois-class homeodomain protein IRX-5(IRX5),Mammalian cell
Code CSB-MP011837HU
Size Pls inquiry other sizes
Source Mammalian cell
Purity >85% (SDS-PAGE)
Tag Info The following tags are available.
N-terminal His-tagged and C-terminal Myc-tagged
N-terminal His-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Sequence MSYPQGYLYQ PSASLALYSC PAYSTSVISG PRTDELGRSS SGSAFSPYAG STAFTAPSPG YNSHLQYGAD PAAAAAAAFS SYVGSPYDHT PGMAGSLGYH PYAAPLGSYP YGDPAYRKNA TRDATATLKA WLNEHRKNPY PTKGEKIMLA IITKMTLTQV STWFANARRR LKKENKMTWT PRNRSEDEEE EENIDLEKND EDEPQKPEDK GDPEGPEAGG AEQKAASGCE RLQGPPTPAG KETEGSLSDS DFKEPPSEGR LDALQGPPRT GGPSPAGPAA ARLAEDPAPH YPAGAPAPGP HPAAGEVPPG PGGPSVIHSP PPPPPPAVLA KPKLWSLAEI ATSSDKVKDG GGGNEGSPCP PCPGPIAGQA LGGSRASPAP APSRSPSAQC PFPGGTVLSR PLYYTAPFYP GYTNYGSFGH LHGHPGPGPG PTTGPGSHFN GLNQTVLNRA DALAKDPKML RSQSQLDLCK DSPYELKKGM SDI
Expression Region 1-483
Protein Description Full length protein
Storage Buffer Tris-based buffer,50% glycerol
Still Have Questions? Leave a Message or Start an on-line Chat

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