Recombinant Human OCIA domain-containing protein 1 (OCIAD1)

Code CSB-YP882129HU
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Source Yeast
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Code CSB-EP882129HU
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Source E.coli
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Code CSB-EP882129HU-B
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Source E.coli
Conjugate Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code CSB-BP882129HU
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Source Baculovirus
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Code CSB-MP882129HU
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Source Mammalian cell
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Product Details

Purity
>85% (SDS-PAGE)
Target Names
OCIAD1
Uniprot No.
Alternative Names
Asrij; FLJ20455; MGC111072 ; OCAD1_HUMAN; OCIA; OCIA domain containing 1; OCIA domain-containing protein 1; OCIAD1; Ovarian carcinoma immunoreactive antigen; TPA018
Species
Homo sapiens (Human)
Expression Region
1-245
Target Protein Sequence
MNGRADFREP NAEVPRPIPH IGPDYIPTEE ERRVFAECND ESFWFRSVPL AATSMLITQG LISKGILSSH PKYGSIPKLI LACIMGYFAG KLSYVKTCQE KFKKLENSPL GEALRSGQAR RSSPPGHYYQ KSKYDSSVSG QSSFVTSPAA DNIEMLPHYE PIPFSSSMNE SAPTGITDHI VQGPDPNLEE SPKRKNITYE ELRNKNRESY EVSLTQKTDP SVRPMHERVP KKEVKVNKYG DTWDE
Protein Length
full length protein
Tag Info
Tag type will be determined during the manufacturing process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form
Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization
Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet
Please contact us to get it.

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Target Background

Function
Maintains stem cell potency. Increases STAT3 phosphorylation and controls ERK phosphorylation. May act as a scaffold, increasing STAT3 recruitment onto endosomes. Involved in integrin-mediated cancer cell adhesion and colony formation in ovarian cancer.
Gene References into Functions
  1. Like OCIAD1, OCIAD2 is a cancer-related protein and its expression level increases during the course of malignant progression and is thought to be a very useful marker for evaluating the malignancy of ovarian mucinous tumors. PMID: 22726067
  2. OCIAD1 is a potential biomarker of thyroid carcinoma but had no significant additive effect on the risk of distant metastasis. PMID: 22081784
  3. This is the first study to indicate that OCIAD1 is a key player in generating ovarian cancer recurrence. PMID: 20515946
  4. Over-expressed in metastatic ovarian cancer. Effect of OCIAD1 on cell adhesion may be related to its function in ovarian cancer. Possibility of OCIAD1's role in tumor metastasis. PMID: 18328549
Subcellular Location
Endosome.
Protein Families
OCIAD1 family
Tissue Specificity
Isoform 1 is highly expressed in many tissues, including testis, brain, placenta, ovary, prostate and mammary gland. Isoform 2 expression is restricted to the central nervous system including brain, cerebellum and spinal cord.
Database Links

HGNC: 16074

KEGG: hsa:54940

STRING: 9606.ENSP00000264312

UniGene: Hs.518750

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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