Recombinant Human Oligodendrocyte-myelin glycoprotein (OMG)

Code CSB-YP016334HU
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Source Yeast
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Code CSB-EP016334HU
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Source E.coli
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Code CSB-EP016334HU-B
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Source E.coli
Conjugate Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code CSB-BP016334HU
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Source Baculovirus
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Code CSB-MP016334HU
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Source Mammalian cell
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Product Details

Purity
>85% (SDS-PAGE)
Target Names
OMG
Uniprot No.
Alternative Names
Oligodendrocyte-myelin glycoprotein; Omg; OMGP ; OMGP_HUMAN
Species
Homo sapiens (Human)
Expression Region
25-417
Target Protein Sequence
ICPLQC ICTERHRHVD CSGRNLSTLP SGLQENIIHL NLSYNHFTDL HNQLTQYTNL RTLDISNNRL ESLPAHLPRS LWNMSAANNN IKLLDKSDTA YQWNLKYLDV SKNMLEKVVL IKNTLRSLEV LNLSSNKLWT VPTNMPSKLH IVDLSNNSLT QILPGTLINL TNLTHLYLHN NKFTFIPDQS FDQLFQLQEI TLYNNRWSCD HKQNITYLLK WMMETKAHVI GTPCSTQISS LKEHNMYPTP SGFTSSLFTV SGMQTVDTIN SLSVVTQPKV TKIPKQYRTK ETTFGATLSK DTTFTSTDKA FVPYPEDTST ETINSHEAAA ATLTIHLQDG MVTNTSLTSS TKSSPTPMTL SITSGMPNNF SEMPQQSTTL NLWREETTTN VKTPLPS
Protein Length
Full Length of Mature Protein
Tag Info
Tag type will be determined during the manufacturing process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form
Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization
Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet
Please contact us to get it.

Citations

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Target Background

Function
Cell adhesion molecule contributing to the interactive process required for myelination in the central nervous system.
Gene References into Functions
  1. The results do not support a relationship between the OMGP gene and the learning disability phenotype observed in neurofibromatosis type 1. PMID: 21534343
  2. novel mutations and novel polymorphisms in coding regions and 5'UTR were detected in patients with with non-syndromic mental retardation PMID: 16425041
  3. Data show that oligodendrocyte-myelin glycoprotein is downregulated in schizophrenia anterior temporal lobe revealed by shotgun proteome analysis. PMID: 19034380
Subcellular Location
Cell membrane; Lipid-anchor, GPI-anchor.
Tissue Specificity
Oligodendrocytes and myelin of the central nervous system.
Database Links

HGNC: 8135

OMIM: 164345

KEGG: hsa:4974

STRING: 9606.ENSP00000247271

UniGene: Hs.113874

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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