Recombinant Human Prostate and breast cancer overexpressed gene 1 protein (PBOV1)

Code CSB-YP861978HU
MSDS
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Source Yeast
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Code CSB-EP861978HU
MSDS
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Source E.coli
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Code CSB-EP861978HU-B
MSDS
Size Pls inquire
Source E.coli
Conjugate Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code CSB-BP861978HU
MSDS
Size Pls inquire
Source Baculovirus
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Code CSB-MP861978HU
MSDS
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Source Mammalian cell
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Product Details

Purity
>85% (SDS-PAGE)
Target Names
PBOV1
Uniprot No.
Alternative Names
BOV 1; PBOV1; PBOV1_HUMAN; Prostate and breast cancer overexpressed 1; Prostate and breast cancer overexpressed gene 1 protein; Protein UROC28; UC28; UROC28
Species
Homo sapiens (Human)
Expression Region
1-135
Target Protein Sequence
MRAFLRNQKY EDMHNIIHIL QIRKLRHRLS NFPRLPGILA PETVLLPFCY KVFRKKEKVK RSQKATEFID YSIEQSHHAI LTPLQTHLTM KGSSMKCSSL SSEAILFTLT LQLTQTLGLE CCLLYLSKTI HPQII
Protein Length
full length protein
Tag Info
Tag type will be determined during the manufacturing process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form
Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization
Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet
Please contact us to get it.

Customer Reviews and Q&A

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Target Background

Gene References into Functions
  1. Study shows that patients with high PBOV1 expression had longer overall survival; patients with low PBOV1 expression had shorter survival suggesting that PBOV1 may play an important role in suppressing ovarian cancer proliferation and carcinogenesis. PMID: 26549570
  2. Data indicate that analysis of public microarray data suggests that PBOV1 activation in tumors could be dependent on the Hedgehog signaling pathway. PMID: 23418531
  3. UROC28 mRNA expression was greater in breast cancers than in noncancerous tissues (p < 0.0001), as was ERBB2 mRNA. PMID: 12553037
  4. Approximately half of the prostate tumors displayed increased copy numbers of the BMP2, BMP5, BMP7, and UC28 gene loci, which may account for their abnormal gene expression patterns in neoplastic prostate tissue. PMID: 17656261
Subcellular Location
Cytoplasm. Nucleus.
Tissue Specificity
Expressed in colon, prostate, small intestine, testis and spleen, with lower expression in thymus, ovary, and peripheral blood leukocytes. Up-regulated expression in prostate, breast, and bladder cancer, but not in lung and colon cancer.
Database Links

HGNC: 21079

OMIM: 605669

KEGG: hsa:59351

UniGene: Hs.302016

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