Recombinant Human Retinitis pigmentosa 9 protein (RP9)

Code CSB-YP844700HU
MSDS
Size Pls inquire
Source Yeast
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Code CSB-EP844700HU
MSDS
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Source E.coli
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Code CSB-EP844700HU-B
MSDS
Size Pls inquire
Source E.coli
Conjugate Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code CSB-BP844700HU
MSDS
Size Pls inquire
Source Baculovirus
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Code CSB-MP844700HU
MSDS
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Source Mammalian cell
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Product Details

Purity
>85% (SDS-PAGE)
Target Names
RP9
Uniprot No.
Alternative Names
PAP-1; Pim-1-associated protein; PIM1-associated protein, mouse, homolog of; Retinitis pigmentosa 9 (human); Retinitis pigmentosa 9 protein; Retinitis pigmentosa 9 protein homolog; rp9; RP9_HUMAN; Rp9h
Species
Homo sapiens (Human)
Expression Region
1-221
Target Protein Sequence
MSSRPGREDV GAAGARRPRE PPEQELQRRR EQKRRRHDAQ QLQQLKHLES FYEKPPPGLI KEDETKPEDC IPDVPGNEHA REFLAHAPTK GLWMPLGKEV KVMQCWRCKR YGHRTGDKEC PFFIKGNQKL EQFRVAHEDP MYDIIRDNKR HEKDVRIQQL KQLLEDSTSD EDRSSSSSSE GKEKHKKKKK KEKHKKRKKE KKKKKKRKHK SSKSNEGSDS E
Protein Length
full length protein
Tag Info
Tag type will be determined during the manufacturing process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form
Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization
Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet
Please contact us to get it.

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Target Background

Function
Is thought to be a target protein for the PIM1 kinase. May play some roles in B-cell proliferation in association with PIM1.
Gene References into Functions
  1. Mutations in a protein target of the Pim-1 kinase associated with the RP9 form of autosomal dominant retinitis pigmentosa PMID: 12032732
  2. Has a role in pre-mRNA splicing, further evidence that PAP-1 is indeed the RP9 gene. PMID: 15474994
  3. PAP-1 interacted with Prp3p but not Prp31p in human cells and yeast, and the basic region of PAP-1 and the C-terminal region of Prp3p, regions beside spots found in retinitis pigmentosa mutations, were needed for binding PMID: 15541726
  4. CIR was found to be colocalized with PAP-1 in nuclear speckles. PMID: 15652350
Involvement in disease
Retinitis pigmentosa 9 (RP9)
Subcellular Location
Nucleus.
Tissue Specificity
Appears to be expressed in a wide range of tissues.
Database Links

HGNC: 10288

OMIM: 180104

KEGG: hsa:6100

STRING: 9606.ENSP00000297157

UniGene: Hs.326805

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