Recombinant Human Serine/threonine-protein kinase 16(STK16)

Code CSB-YP022835HU
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Source Yeast
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Code CSB-EP022835HU-B
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Source E.coli
Conjugate Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code CSB-BP022835HU
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Source Baculovirus
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Code CSB-MP022835HU
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Source Mammalian cell
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Product Details

Purity >85% (SDS-PAGE)
Target Names STK16
Uniprot No. O75716
Alternative Names EDPK; F52; FLJ39635; hPSK; KRCT; MGC16211; MPSK; MPSK1; Myristoylated and palmitoylated serine/threonine protein kinase; Myristoylated and palmitoylated serine/threonine-protein kinase; PKL12 ; Protein kinase expressed in day 12 fetal liver ; Protein kinase Krct; Protein kinase PKL12; Serine/threonine kinase 16 ; Serine/threonine protein kinase 16; Serine/threonine-protein kinase 16; Stk16; STK16_HUMAN; TGF beta stimulated factor 1; TGF-beta-stimulated factor 1; TGFB stimulated factor 1; Transforming growth factor beta stimulated factor 1; TSF-1; TSF1; Tyrosine protein kinase STK16
Species Homo sapiens (Human)
Expression Region 2-305
Target Protein Sequence GHALCVCSR GTVIIDNKRY LFIQKLGEGG FSYVDLVEGL HDGHFYALKR ILCHEQQDRE EAQREADMHR LFNHPNILRL VAYCLRERGA KHEAWLLLPF FKRGTLWNEI ERLKDKGNFL TEDQILWLLL GICRGLEAIH AKGYAHRDLK PTNILLGDEG QPVLMDLGSM NQACIHVEGS RQALTLQDWA AQRCTISYRA PELFSVQSHC VIDERTDVWS LGCVLYAMMF GEGPYDMVFQ KGDSVALAVQ NQLSIPQSPR HSSALRQLLN SMMTVDPHQR PHIPLLLSQL EALQPPAPGQ HTTQI
Protein Length Full Length of Mature Protein
Tag Info The following tags are available.
N-terminal His-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form Lyophilized powder
Buffer before Lyophilization Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting
and FAQs
Protein FAQs
Storage Condition Store at -20°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet Please contact us to get it.

Target Data

Function Membrane-associated protein kinase that phosphorylates on serine and threonine residues. In vitro substrates include DRG1, ENO1 and EIF4EBP1. Also autophosphorylates. May be involved in secretory vesicle trafficking or intracellular signaling. May have a role in regulating stromal-epithelial interactions that occur during ductal morphogenesis in the mammary gland. May be involved in TGF-beta signaling. Able to autophosphorylate on Tyr residue; it is however unclear whether it has tyrosine-protein kinase toward other proteins.
Gene References into Functions
  1. we revealed STK16 as a novel actin binding protein that resides in the Golgi, which regulates actin dynamics to control Golgi structure and participate in cell cycle progression. PMID: 28294156
  2. MAL2 and STK16 function to sort secretory soluble cargo into the constitutive secretory pathway in hepatocytes. PMID: 25084525
  3. The Endogenous STK16 subcellular localization was evaluated by indirect immunofluorescence in NRK cells, demonstrating a Golgi-associated pattern that appears to be independent of signals provided by integrin pathways. PMID: 16310770
Subcellular Location Cytoplasm, perinuclear region, Membrane, Lipid-anchor
Protein Families Protein kinase superfamily, Ser/Thr protein kinase family
Tissue Specificity Ubiquitously expressed at very low levels.
Database Links

HGNC: 11394

OMIM: 604719

KEGG: hsa:8576

STRING: 9606.ENSP00000379964

UniGene: Hs.153003

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