Recombinant Human Short-chain dehydrogenase/reductase family 9C member 7 (SDR9C7)

Code CSB-YP854114HU
MSDS
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Source Yeast
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Code CSB-EP854114HU
MSDS
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Source E.coli
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Code CSB-EP854114HU-B
MSDS
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Source E.coli
Conjugate Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code CSB-BP854114HU
MSDS
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Source Baculovirus
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Code CSB-MP854114HU
MSDS
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Source Mammalian cell
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Product Details

Purity
>85% (SDS-PAGE)
Target Names
SDR9C7
Uniprot No.
Alternative Names
SDR9C7; RDHS; SDROShort-chain dehydrogenase/reductase family 9C member 7; EC 1.1.1.-; Orphan short-chain dehydrogenase/reductase; SDR-O; RDH-S
Species
Homo sapiens (Human)
Expression Region
1-313
Target Protein Sequence
MAALTDLSFM YRWFKNCNLV GNLSEKYVFI TGCDSGFGNL LAKQLVDRGM QVLAACFTEE GSQKLQRDTS YRLQTTLLDV TKSESIKAAA QWVRDKVGEQ GLWALVNNAG VGLPSGPNEW LTKDDFVKVI NVNLVGLIEV TLHMLPMVKR ARGRVVNMSS SGGRVAVIGG GYCVSKFGVE AFSDSIRREL YYFGVKVCII EPGNYRTAIL GKENLESRMR KLWERLPQET RDSYGEDYFR IYTDKLKNIM QVAEPRVRDV INSMEHAIVS RSPRIRYNPG LDAKLLYIPL AKLPTPVTDF ILSRYLPRPA DSV
Protein Length
full length protein
Tag Info
Tag type will be determined during the manufacturing process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form
Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization
Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet
Please contact us to get it.

Customer Reviews and Q&A

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Target Background

Function
Displays weak conversion of all-trans-retinal to all-trans-retinol in the presence of NADH. Has apparently no steroid dehydrogenase activity.
Gene References into Functions
  1. Missense mutations in SDR9C7 gene were identified in families with autosomal recessive congenital ichthyosis: two families shared an identical homozygous mutation c.599T > C (p.Ile200Thr) and one family had another homozygous mutation c.214C > T (p.Arg72Trp). The mutations severely affected a stability of the protein. In a patient's skin, SDR9C7 gene expression in the cornified layer was decreased. PMID: 28173123
  2. SDR9C7 promotes esophageal squamous cell carcinoma metastasis partly through regulation of MMP11. PMID: 23341893
Involvement in disease
Ichthyosis, congenital, autosomal recessive 13 (ARCI13)
Subcellular Location
Cytoplasm. Note=Granular distribution in the whole cell.
Protein Families
Short-chain dehydrogenases/reductases (SDR) family
Tissue Specificity
Expressed in the skin. Expressed in granular and cornified layers of the epidermis (at protein level). Highly expressed in liver.
Database Links

HGNC: 29958

OMIM: 609769

KEGG: hsa:121214

STRING: 9606.ENSP00000293502

UniGene: Hs.380178

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