Recombinant Human Small subunit processome component 20 homolog (UTP20), partial

Code CSB-YP025766HU
MSDS
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Source Yeast
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Code CSB-EP025766HU
MSDS
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Source E.coli
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Code CSB-EP025766HU-B
MSDS
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Source E.coli
Conjugate Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code CSB-BP025766HU
MSDS
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Source Baculovirus
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Code CSB-MP025766HU
MSDS
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Source Mammalian cell
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Product Details

Purity
>85% (SDS-PAGE)
Target Names
UTP20
Uniprot No.
Alternative Names
UTP20; DRIM; Small subunit processome component 20 homolog; Down-regulated in metastasis protein; Novel nucleolar protein 73; NNP73; Protein Key-1A6
Species
Homo sapiens (Human)
Protein Length
Partial
Tag Info
Tag type will be determined during the manufacturing process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form
Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization
Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet
Please contact us to get it.

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Target Background

Function
Involved in 18S pre-rRNA processing. Associates with U3 snoRNA.
Gene References into Functions
  1. 1A6/DRIM activates Pol I transcription most likely by associating with both hALP and UBF and thereby affecting the acetylation of UBF PMID: 21151873
  2. Analysis of the relationship between DRIM gene expression and the metastatic phenotype of breast neoplasms. PMID: 14503924
  3. a single region located between amino acids 2744 and 2761 at the C-terminus is capable of nucleolar accumulation. Two basic amino acid clusters within this region are essential for nucleolar accumulation. PMID: 16458307
  4. DRIM is involved in 18S rRNA processing PMID: 17498821
Subcellular Location
Nucleus, nucleolus. Note=Colocalizes with NCL in the nucleolus.
Protein Families
UTP20 family
Tissue Specificity
Expressed in appendix, brain, colon, fetal liver, heart, ovary, pancreas, placenta, prostate, skeletal muscle, small intestine, spleen, testis and thymus.
Database Links

HGNC: 17897

OMIM: 612822

KEGG: hsa:27340

STRING: 9606.ENSP00000261637

UniGene: Hs.295732

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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