Recombinant Human Transcription initiation protein SPT3 homolog (SUPT3H)

Code CSB-YP022956HU
MSDS
Size Pls inquire
Source Yeast
Have Questions? Leave a Message or Start an on-line Chat
Code CSB-EP022956HU-B
MSDS
Size Pls inquire
Source E.coli
Conjugate Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
Have Questions? Leave a Message or Start an on-line Chat
Code CSB-BP022956HU
MSDS
Size Pls inquire
Source Baculovirus
Have Questions? Leave a Message or Start an on-line Chat
Code CSB-MP022956HU
MSDS
Size Pls inquire
Source Mammalian cell
Have Questions? Leave a Message or Start an on-line Chat

Product Details

Purity
>85% (SDS-PAGE)
Target Names
SUPT3H
Uniprot No.
Alternative Names
SUPT3H; SPT3; Transcription initiation protein SPT3 homolog; SPT3-like protein
Species
Homo sapiens (Human)
Expression Region
1-399
Target Protein Sequence
MYSPRGSQGR GTAEATANSP SPPIAPSHSR VTFSLSTLHT LSPPPRPFPS VSRAAAQKPH HLHPHILLAG SAAVPPRVLK AEMNNTAASP MSTATSSSGR STGKSISFAT ELQSMMYSLG DARRPLHETA VLVEDVVHTQ LINLLQQAAE VSQLRGARVI TPEDLLFLMR KDKKKLRRLL KYMFIRDYKS KIVKGIDEDD LLEDKLSGSN NANKRQKIAQ DFLNSIDQTG ELLAMFEDDE IDEVKQERME RAERQTRIMD SAQYAEFCES RQLSFSKKAS KFRDWLDCSS MEIKPNVVAM EILAYLAYET VAQLVDLALL VRQDMVTKAG DPFSHAISAT FIQYHNSAES TAACGVEAHS DAIQPCHIRE AIRRYSHRIG PLSPFTNAYR RNGMAFLAC
Protein Length
Full length protein
Tag Info
Tag type will be determined during the manufacturing process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form
Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization
Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet
Please contact us to get it.

Customer Reviews and Q&A

 Customer Reviews

There are currently no reviews for this product.

Submit a Review here

Target Background

Function
Probable transcriptional activator.
Gene References into Functions
  1. significance of the formation PVT1- SUPT3H chimeric gene remains unknown and the overexpression of MYC by ectopic promoter on chromosome 6 may be essential to tumor genesis. PMID: 25860292
  2. we identified rs41314453 as the main genetic determinant of ADAMTS13 activity, and we present preliminary findings for further associations at the ADAMTS13 and SUPT3H loci. PMID: 25934476
  3. identified a significant excess of genes with pivotal roles in bone homeostasis, such as PPPT3B and the height associated SUPT3H-RUNX2 PMID: 22407027
  4. suggest a novel STAF65gamma-dependent function of STAGA-type complexes in cell proliferation and transcription activation by MYC postloading of TFIID and RNA polymerase II that involves direct recruitment of core Mediator PMID: 17967894
  5. Found evidence of Mendelian Transmission Distortion in the region harboring SUPT3H in one HapMap population. PMID: 19259136

Show More

Hide All

Subcellular Location
Nucleus.
Protein Families
SPT3 family
Tissue Specificity
Expressed in all tissues tested including pancreas, kidney, skeletal muscle, liver, lung, placenta, brain and heart.
Database Links

HGNC: 11466

OMIM: 602947

STRING: 9606.ENSP00000360515

UniGene: Hs.368325

icon of phone
Call us
301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
icon of address
Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
icon of social media
Join us with

Subscribe newsletter

Leave a message

* To protect against spam, please pass the CAPTCHA test below.
CAPTCHA verification
© 2007-2024 CUSABIO TECHNOLOGY LLC All rights reserved. 鄂ICP备15011166号-1