Recombinant Human Uncharacterized protein C1orf96 (C1orf96)

Code CSB-YP743584HU
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Source Yeast
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Code CSB-EP743584HU
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Source E.coli
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Code CSB-EP743584HU-B
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Source E.coli
Conjugate Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code CSB-BP743584HU
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Source Baculovirus
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Code CSB-MP743584HU
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Source Mammalian cell
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Product Details

Purity
>85% (SDS-PAGE)
Target Names
CCSAP
Uniprot No.
Alternative Names
CCSAP; C1orf96; CSAPCentriole; cilia and spindle-associated protein
Species
Homo sapiens (Human)
Expression Region
1-270
Target Protein Sequence
MSPGSGVKSE YMKRYQEPRW EEYGPCYREL LHYRLGRRLL EQAHAPWLWD DWGPAGSSED SASSESSGAG GPAPRCAPPS PPPPVEPATQ EEAERRARGA PEEQDAEAGD AEAEDAEDAA LPALPVKDVE DKPEQQTRTR ETDKSPTSTE PRQQPSALFA RGNRKAVKSP QRSSSKIKEN KHPFALYGWG EKQTDTGSQK THNVCASAPV HEIHESALRA KNRRQVEKRK LVAQRQRAHS VDVEKNRKMK ASSSENPWMT EYMRCYSARA
Protein Length
full length protein
Tag Info
Tag type will be determined during the manufacturing process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form
Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization
Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet
Please contact us to get it.

Customer Reviews and Q&A

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Target Background

Function
Plays a role in microtubule (MT) stabilization and this stabilization involves the maintenance of NUMA1 at the spindle poles. Colocalizes with polyglutamylated MTs to promote MT stabilization and regulate bipolar spindle formation in mitosis. Binding of CCSAP to centrosomes and the spindle around centrosomes during mitosis inhibits MT depolymerization, thereby stabilizing the mitotic spindle. May play a role in embryonic development. May be required for proper cilia beating.
Gene References into Functions
  1. The tubulin binding protein CSAP associates with mitotic microtubules around centrosomes to stabilize mitotic microtubules during mitosis, ensuring proper bipolar spindle formation and maintenance. PMID: 26562023
Subcellular Location
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, cilium basal body. Cytoplasm, cytoskeleton, cilium axoneme. Cell projection, axon. Cell projection, cilium. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.
Protein Families
CCSAP family
Database Links

HGNC: 29578

KEGG: hsa:126731

STRING: 9606.ENSP00000284617

UniGene: Hs.585011

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