Recombinant Influenza A virus Nucleoprotein(NP)

Product Type Recombinant Protein
Uniprot No. P16986
Species Influenza A virus (strain A/Swine/Hong Kong/6/1976 H3N2)
Gene Names NP
Protein Names Recommended name: Nucleoprotein Alternative name(s): Nucleocapsid protein Short name= Protein N
Storage The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Function Encapsidates the negative strand viral RNA, protecting it from nucleases. The encapsidated genomic RNA is termed the ribonucleoprotein (RNP) and serves as template for transcription and replication. The RNP needs to be localized in the host nucleus to start an infectious cycle, but is too large to diffuse through the nuclear pore complex. NP comprises at least 2 nuclear localization signals that are responsible for the active RNP import into the nucleus through cellular importin alpha/beta pathway. Later in the infection, nclear export of RNPs are mediated through viral proteins NEP interacting with M1 which binds nucleoproteins. It is possible that nucleoprotein binds directly host exportin-1/XPO1 and plays an active role in RNPs nuclear export. M1 interaction with RNP seems to hide nucleoprotein's nuclear localization signals. Soon after a virion infects a new cell, M1 dissociates from the RNP under acidification of the virion driven by M2 protein. Dissociation of M1 from RNP unmasks nucleoprotein's nuclear localization signals, targeting the RNP to the nucleus.
Subcellular Location Virion, Host nucleus
Protein Families Influenza viruses nucleoprotein family

Product Details for Different Expression Systems

Product Name Recombinant Influenza A virus Nucleoprotein(NP),Yeast
Code CSB-YP322328IGU
Size Pls inquiry other sizes
Source Yeast
Purity >85% (SDS-PAGE)
Tag Info The following tags are available.
N-terminal His-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Sequence MASQGTKRSY EQMETDGERQ NATEIRASVG KMINGIGRFY IQMCTELKLS DYEGRLIQNS LTIERMVLSA FDERRNKYLE EHPSAGKDPK KTGGPIYKRV DGKWMRELVL YDKEEMRRIW RQANNGDDAT AGLTHLMIWH SNLNDTTYQR TRALVRTGMD PRMCSLMQGS TLPRRSGAAG AAVKGVGTMV MELIRMIKRG INDRNFWRGE NGRKTRSAYE RMCNILKGKF QTAAQRAMMD QVRESRNPGN AEIEDLIFLA RSALILRGSV AHKSCLPACV YGPAVASGYD FEKEGYSLVG IDPFKLLQNS QVYSLIRPNE NPAHKSQLVW MACNSAAFED LRVLSFIRGT KVSPRGKLST RGVQIASNEN MDTMESSTLE LRSRYWAIRT RSGGNTNQQR ASAGQISVQP AFSVQRNLPF DKPTIMAAFT GNTEGRTSDM RTEIIRMMEG AKPEEMSFQG RGVFELSDEK ATNPIVPSFD MSNEGSYFFG DNAEEYDN
Expression Region 1-498
Protein Description full length protein
Storage Buffer Tris-based buffer,50% glycerol
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Product Name Recombinant Influenza A virus Nucleoprotein(NP),E.coli
Code CSB-EP322328IGU
Size Pls inquiry other sizes
Source E.coli
Purity >85% (SDS-PAGE)
Tag Info The following tags are available.
N-terminal His-tagged and C-terminal Myc-tagged
N-terminal His-SUMO-tagged and C-terminal Myc-tagged
N-terminal His-B2M-tagged and C-terminal Myc-tagged
N-terminal His-GST-tagged and C-terminal Myc-tagged
N-terminal His-tagged
N-terminal His-SUMO-tagged
N-terminal His-B2M-tagged
N-terminal His-GST-tagged
N-terminal GST-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Sequence MASQGTKRSY EQMETDGERQ NATEIRASVG KMINGIGRFY IQMCTELKLS DYEGRLIQNS LTIERMVLSA FDERRNKYLE EHPSAGKDPK KTGGPIYKRV DGKWMRELVL YDKEEMRRIW RQANNGDDAT AGLTHLMIWH SNLNDTTYQR TRALVRTGMD PRMCSLMQGS TLPRRSGAAG AAVKGVGTMV MELIRMIKRG INDRNFWRGE NGRKTRSAYE RMCNILKGKF QTAAQRAMMD QVRESRNPGN AEIEDLIFLA RSALILRGSV AHKSCLPACV YGPAVASGYD FEKEGYSLVG IDPFKLLQNS QVYSLIRPNE NPAHKSQLVW MACNSAAFED LRVLSFIRGT KVSPRGKLST RGVQIASNEN MDTMESSTLE LRSRYWAIRT RSGGNTNQQR ASAGQISVQP AFSVQRNLPF DKPTIMAAFT GNTEGRTSDM RTEIIRMMEG AKPEEMSFQG RGVFELSDEK ATNPIVPSFD MSNEGSYFFG DNAEEYDN
Expression Region 1-498
Protein Description full length protein
Storage Buffer Tris-based buffer,50% glycerol
Still Have Questions? Leave a Message or Start an on-line Chat
Product Name Recombinant Influenza A virus Nucleoprotein(NP),Baculovirus
Code CSB-BP322328IGU
Size Pls inquiry other sizes
Source Baculovirus
Purity >85% (SDS-PAGE)
Tag Info The following tags are available.
N-terminal His-tagged and C-terminal Myc-tagged
N-terminal His-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Sequence MASQGTKRSY EQMETDGERQ NATEIRASVG KMINGIGRFY IQMCTELKLS DYEGRLIQNS LTIERMVLSA FDERRNKYLE EHPSAGKDPK KTGGPIYKRV DGKWMRELVL YDKEEMRRIW RQANNGDDAT AGLTHLMIWH SNLNDTTYQR TRALVRTGMD PRMCSLMQGS TLPRRSGAAG AAVKGVGTMV MELIRMIKRG INDRNFWRGE NGRKTRSAYE RMCNILKGKF QTAAQRAMMD QVRESRNPGN AEIEDLIFLA RSALILRGSV AHKSCLPACV YGPAVASGYD FEKEGYSLVG IDPFKLLQNS QVYSLIRPNE NPAHKSQLVW MACNSAAFED LRVLSFIRGT KVSPRGKLST RGVQIASNEN MDTMESSTLE LRSRYWAIRT RSGGNTNQQR ASAGQISVQP AFSVQRNLPF DKPTIMAAFT GNTEGRTSDM RTEIIRMMEG AKPEEMSFQG RGVFELSDEK ATNPIVPSFD MSNEGSYFFG DNAEEYDN
Expression Region 1-498
Protein Description full length protein
Storage Buffer Tris-based buffer,50% glycerol
Still Have Questions? Leave a Message or Start an on-line Chat
Product Name Recombinant Influenza A virus Nucleoprotein(NP),Mammalian cell
Code CSB-MP322328IGU
Size Pls inquiry other sizes
Source Mammalian cell
Purity >85% (SDS-PAGE)
Tag Info The following tags are available.
N-terminal His-tagged and C-terminal Myc-tagged
N-terminal His-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Sequence MASQGTKRSY EQMETDGERQ NATEIRASVG KMINGIGRFY IQMCTELKLS DYEGRLIQNS LTIERMVLSA FDERRNKYLE EHPSAGKDPK KTGGPIYKRV DGKWMRELVL YDKEEMRRIW RQANNGDDAT AGLTHLMIWH SNLNDTTYQR TRALVRTGMD PRMCSLMQGS TLPRRSGAAG AAVKGVGTMV MELIRMIKRG INDRNFWRGE NGRKTRSAYE RMCNILKGKF QTAAQRAMMD QVRESRNPGN AEIEDLIFLA RSALILRGSV AHKSCLPACV YGPAVASGYD FEKEGYSLVG IDPFKLLQNS QVYSLIRPNE NPAHKSQLVW MACNSAAFED LRVLSFIRGT KVSPRGKLST RGVQIASNEN MDTMESSTLE LRSRYWAIRT RSGGNTNQQR ASAGQISVQP AFSVQRNLPF DKPTIMAAFT GNTEGRTSDM RTEIIRMMEG AKPEEMSFQG RGVFELSDEK ATNPIVPSFD MSNEGSYFFG DNAEEYDN
Expression Region 1-498
Protein Description full length protein
Storage Buffer Tris-based buffer,50% glycerol
Still Have Questions? Leave a Message or Start an on-line Chat

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