Recombinant Listeria monocytogenes serotype 1/2a Listeriolysin O(hly) ,partial

Product Type Recombinant Protein
Uniprot No. D2PAJ7
Species Listeria monocytogenes serotype 1/2a (strain 08-5923)
Gene Names hly
Protein Names Recommended name: Listeriolysin O Alternative name(s): LLO Thiol-activated cytolysin
Storage The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Function Sulfhydryl-activated toxin that causes cytolysis by forming pores in cholesterol containing host membranes. After binding to target membranes, the protein undergoes a major conformation change, leading to its insertion in the host membrane and formation of an oligomeric pore complex. Cholesterol may be required for binding to host membranes, membrane insertion and pore formation. Acts as major virulence factor required for the escape of bacteria from phagosomal vacuoles and entry into the host cytosol. Can be reversibly inactivated by oxidation (By similarity).
Subcellular Location Secreted, Host membrane, Multi-pass membrane protein, Host cell membrane, Multi-pass membrane protein
Protein Families Thiol-activated cytolysin family
Database Links

KEGG: lmy:LM5923_2765

Product Details for Different Expression Systems

Product Name Recombinant Listeria monocytogenes serotype 1/2a Listeriolysin O(hly) ,partial,Yeast
Code CSB-YP512167LPV
Size Pls inquiry other sizes
Source Yeast
Purity >85% (SDS-PAGE)
Tag Info The following tags are available.
N-terminal His-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Storage Buffer Tris-based buffer,50% glycerol
Still Have Questions? Leave a Message or Start an on-line Chat
Product Name Recombinant Listeria monocytogenes serotype 1/2a Listeriolysin O(hly) ,partial,E.coli
Code CSB-EP512167LPV
Size Pls inquiry other sizes
Source E.coli
Purity >85% (SDS-PAGE)
Tag Info The following tags are available.
N-terminal His-tagged and C-terminal Myc-tagged
N-terminal His-SUMO-tagged and C-terminal Myc-tagged
N-terminal His-B2M-tagged and C-terminal Myc-tagged
N-terminal His-GST-tagged and C-terminal Myc-tagged
N-terminal His-tagged
N-terminal His-SUMO-tagged
N-terminal His-B2M-tagged
N-terminal His-GST-tagged
N-terminal GST-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Storage Buffer Tris-based buffer,50% glycerol
Still Have Questions? Leave a Message or Start an on-line Chat
Product Name Recombinant Listeria monocytogenes serotype 1/2a Listeriolysin O(hly) ,partial,Baculovirus
Code CSB-BP512167LPV
Size Pls inquiry other sizes
Source Baculovirus
Purity >85% (SDS-PAGE)
Tag Info The following tags are available.
N-terminal His-tagged and C-terminal Myc-tagged
N-terminal His-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Storage Buffer Tris-based buffer,50% glycerol
Still Have Questions? Leave a Message or Start an on-line Chat
Product Name Recombinant Listeria monocytogenes serotype 1/2a Listeriolysin O(hly) ,partial,Mammalian cell
Code CSB-MP512167LPV
Size Pls inquiry other sizes
Source Mammalian cell
Purity >85% (SDS-PAGE)
Tag Info The following tags are available.
N-terminal His-tagged and C-terminal Myc-tagged
N-terminal His-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Storage Buffer Tris-based buffer,50% glycerol
Still Have Questions? Leave a Message or Start an on-line Chat

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