Recombinant Macaca fascicularis Interferon-induced protein with tetratricopeptide repeats 1 (IFIT1)

Code CSB-YP011018MOV
MSDS
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Source Yeast
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Code CSB-EP011018MOV
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Source E.coli
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Code CSB-EP011018MOV-B
MSDS
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Source E.coli
Conjugate Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code CSB-BP011018MOV
MSDS
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Source Baculovirus
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Code CSB-MP011018MOV
MSDS
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Source Mammalian cell
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Product Details

Purity
>85% (SDS-PAGE)
Target Names
IFIT1
Uniprot No.
Alternative Names
IFIT1; QnpA-13470Interferon-induced protein with tetratricopeptide repeats 1; IFIT-1
Species
Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)
Expression Region
1-478
Target Protein Sequence
MSTNGDNHQV KDSLEQLRCH FTWELFIEDD EMPDLENRVL DQIEFLDTKY NVGIHNLLAY VKHLKGQNEE ALKSLKEAED LMQKEHANQA SVRSLVTWSN FAWVYYHMGR LAEAQAYLDK VENICKKPSN PFRYRMECPE IDCEEGWALL KCGGKNYERA KACFEKALEG DHENPEFSTG YAISAYRLDG FKLATKGYRQ FSLLPLRQAV SLNPDNGYLK VLLALKLQDN GQEAEGEKYL EEALANMSSQ TYVFRYAAKF YRRKGSVDKA LELLKKALQE TPTSVLLHHQ IGLCYKAQMI QIKEATKGQP RGQNREKIDK MIRLAIFHFE SAVENKPTFE VAHLDLARMY IEAGNHRKAE ETFQKLLCMK PVVEETMQDI HLQYARFQEF QKKSEINAII HYLKAIKIEQ TSFIRDKSIN SLKKLVLKKL QRNALDLESL SLLGFVYKLK GNMNEALEYY ERALRLAADF ENSVRQGP
Protein Length
full length protein
Tag Info
Tag type will be determined during the manufacturing process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form
Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization
Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet
Please contact us to get it.

Customer Reviews and Q&A

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Target Background

Function
Interferon-induced antiviral RNA-binding protein that specifically binds single-stranded RNA bearing a 5'-triphosphate group (PPP-RNA), thereby acting as a sensor of viral single-stranded RNAs and inhibiting expression of viral messenger RNAs. Single-stranded PPP-RNAs, which lack 2'-O-methylation of the 5' cap and bear a 5'-triphosphate group instead, are specific from viruses, providing a molecular signature to distinguish between self and non-self mRNAs by the host during viral infection. Directly binds PPP-RNA in a non-sequence-specific manner. Viruses evolved several ways to evade this restriction system such as encoding their own 2'-O-methylase for their mRNAs or by stealing host cap containing the 2'-O-methylation (cap snatching mechanism).
Subcellular Location
Cytoplasm.
Protein Families
IFIT family
Database Links

KEGG: mcf:102143994

UniGene: Mfa.8396

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