Recombinant Mouse CTP synthase 2(Ctps2)

Product Type Recombinant Protein
Uniprot No. P70303
Species Mus musculus (Mouse)
Gene Names Ctps2
Protein Names Recommended name: CTP synthase 2 EC= 6.3.4.2 Alternative name(s): CTP synthetase 2 Short name= CTPsH UTP--ammonia ligase 2
Storage Store at -20°C, for extended storage, conserve at -20°C or -80°C.
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Target Details This protein catalyzes the formation of CTP from UTP with the concomitant deamination of glutamine to glutamate. This protein is the rate-limiting enzyme in the synthesis of cytosine nucleotides, which play an important role in various metabolic processes and provide the precursors necessary for the synthesis of RNA and DNA. Cancer cells that exhibit increased cell proliferation also exhibit an increased activity of this encoded protein. Thus, this protein is an attractive target for selective chemotherapy. Three alternatively spliced transcript variants encoding the same protein have been described for this gene.
HGNC 2520
RGD 1563369
MGI 1933185
Function Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Constitutes the rate-limiting enzyme in the synthesis of cytosine nucleotides (By similarity).
Protein Families CTP synthase family
Database Links

KEGG: mmu:55936

STRING: 10090.ENSMUSP00000033727

UniGene: Mm.2065

Product Details for Different Expression Systems

Product Name Recombinant Mouse CTP synthase 2(Ctps2),Yeast
Code CSB-YP006177MO
Size Pls inquiry other sizes
Source Yeast
Purity >85% (SDS-PAGE)
Tag Info The following tags are available.
N-terminal His-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Sequence MKYILVTGGV ISGIGKGIIA SSIGTILKSC GLRVTAIKID PYINIDAGTF SPYEHGEVFV LNDGGEVDLD LGNYERFLDI NLYKDNNITT GKIYQHVINK ERRGDYLGKT VQVVPHITDA IQEWVMNQAK VSVDGNKEDP QICVIELGGT IGDIEGMAFV EAFRQFQFKA KKENFYNIHV SLVPQPSATG EQKTKPTQNS VRALRGLGLS PDLIVCRSST PIEMAVKEKI SMFCHVNPEQ VICIHDVSSI YRVPLLLEEQ GVVKYFQERL GLPINDCSSN LLFKWKAMAD RYERLQKICS IALVGKYTKL RDCYASVFKA LEHSALAINH KLNLMYIDSI DLEPVTKAED PVKFHEAWQK LCLADGILVP GGFGIRGTLG KLQAISWART KKIPFLGICL GMQLAVIEFA RNCLNLKDAN STEFEPNTPV PLVIDMPEHN PGDLGGTMRL GLRRTVFTTE NSILKKLYGD VPYIEERHRH RYEVNPNLIN QFENKDLCFV GEDVDGKRME IVELTSHPYF IGVQFHPEFS SRPMKPSPPY LGLLLAATGN LNAHLQQMNK LPYSDGYSDA SDDSFPEAKL AELDLN
Expression Region 1-586
Protein Description Full length protein
Storage Buffer Tris-based buffer,50% glycerol
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Product Name Recombinant Mouse CTP synthase 2(Ctps2),E.coli
Code CSB-EP006177MO
Size Pls inquiry other sizes
Source E.coli
Purity >85% (SDS-PAGE)
Tag Info The following tags are available.
N-terminal His-tagged and C-terminal Myc-tagged
N-terminal His-SUMO-tagged and C-terminal Myc-tagged
N-terminal His-B2M-tagged and C-terminal Myc-tagged
N-terminal His-GST-tagged and C-terminal Myc-tagged
N-terminal His-tagged
N-terminal His-SUMO-tagged
N-terminal His-B2M-tagged
N-terminal His-GST-tagged
N-terminal GST-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Sequence MKYILVTGGV ISGIGKGIIA SSIGTILKSC GLRVTAIKID PYINIDAGTF SPYEHGEVFV LNDGGEVDLD LGNYERFLDI NLYKDNNITT GKIYQHVINK ERRGDYLGKT VQVVPHITDA IQEWVMNQAK VSVDGNKEDP QICVIELGGT IGDIEGMAFV EAFRQFQFKA KKENFYNIHV SLVPQPSATG EQKTKPTQNS VRALRGLGLS PDLIVCRSST PIEMAVKEKI SMFCHVNPEQ VICIHDVSSI YRVPLLLEEQ GVVKYFQERL GLPINDCSSN LLFKWKAMAD RYERLQKICS IALVGKYTKL RDCYASVFKA LEHSALAINH KLNLMYIDSI DLEPVTKAED PVKFHEAWQK LCLADGILVP GGFGIRGTLG KLQAISWART KKIPFLGICL GMQLAVIEFA RNCLNLKDAN STEFEPNTPV PLVIDMPEHN PGDLGGTMRL GLRRTVFTTE NSILKKLYGD VPYIEERHRH RYEVNPNLIN QFENKDLCFV GEDVDGKRME IVELTSHPYF IGVQFHPEFS SRPMKPSPPY LGLLLAATGN LNAHLQQMNK LPYSDGYSDA SDDSFPEAKL AELDLN
Expression Region 1-586
Protein Description Full length protein
Storage Buffer Tris-based buffer,50% glycerol
Still Have Questions? Leave a Message or Start an on-line Chat
Product Name Recombinant Mouse CTP synthase 2(Ctps2),Baculovirus
Code CSB-BP006177MO
Size Pls inquiry other sizes
Source Baculovirus
Purity >85% (SDS-PAGE)
Tag Info The following tags are available.
N-terminal His-tagged and C-terminal Myc-tagged
N-terminal His-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Sequence MKYILVTGGV ISGIGKGIIA SSIGTILKSC GLRVTAIKID PYINIDAGTF SPYEHGEVFV LNDGGEVDLD LGNYERFLDI NLYKDNNITT GKIYQHVINK ERRGDYLGKT VQVVPHITDA IQEWVMNQAK VSVDGNKEDP QICVIELGGT IGDIEGMAFV EAFRQFQFKA KKENFYNIHV SLVPQPSATG EQKTKPTQNS VRALRGLGLS PDLIVCRSST PIEMAVKEKI SMFCHVNPEQ VICIHDVSSI YRVPLLLEEQ GVVKYFQERL GLPINDCSSN LLFKWKAMAD RYERLQKICS IALVGKYTKL RDCYASVFKA LEHSALAINH KLNLMYIDSI DLEPVTKAED PVKFHEAWQK LCLADGILVP GGFGIRGTLG KLQAISWART KKIPFLGICL GMQLAVIEFA RNCLNLKDAN STEFEPNTPV PLVIDMPEHN PGDLGGTMRL GLRRTVFTTE NSILKKLYGD VPYIEERHRH RYEVNPNLIN QFENKDLCFV GEDVDGKRME IVELTSHPYF IGVQFHPEFS SRPMKPSPPY LGLLLAATGN LNAHLQQMNK LPYSDGYSDA SDDSFPEAKL AELDLN
Expression Region 1-586
Protein Description Full length protein
Storage Buffer Tris-based buffer,50% glycerol
Still Have Questions? Leave a Message or Start an on-line Chat
Product Name Recombinant Mouse CTP synthase 2(Ctps2),Mammalian cell
Code CSB-MP006177MO
Size Pls inquiry other sizes
Source Mammalian cell
Purity >85% (SDS-PAGE)
Tag Info The following tags are available.
N-terminal His-tagged and C-terminal Myc-tagged
N-terminal His-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Sequence MKYILVTGGV ISGIGKGIIA SSIGTILKSC GLRVTAIKID PYINIDAGTF SPYEHGEVFV LNDGGEVDLD LGNYERFLDI NLYKDNNITT GKIYQHVINK ERRGDYLGKT VQVVPHITDA IQEWVMNQAK VSVDGNKEDP QICVIELGGT IGDIEGMAFV EAFRQFQFKA KKENFYNIHV SLVPQPSATG EQKTKPTQNS VRALRGLGLS PDLIVCRSST PIEMAVKEKI SMFCHVNPEQ VICIHDVSSI YRVPLLLEEQ GVVKYFQERL GLPINDCSSN LLFKWKAMAD RYERLQKICS IALVGKYTKL RDCYASVFKA LEHSALAINH KLNLMYIDSI DLEPVTKAED PVKFHEAWQK LCLADGILVP GGFGIRGTLG KLQAISWART KKIPFLGICL GMQLAVIEFA RNCLNLKDAN STEFEPNTPV PLVIDMPEHN PGDLGGTMRL GLRRTVFTTE NSILKKLYGD VPYIEERHRH RYEVNPNLIN QFENKDLCFV GEDVDGKRME IVELTSHPYF IGVQFHPEFS SRPMKPSPPY LGLLLAATGN LNAHLQQMNK LPYSDGYSDA SDDSFPEAKL AELDLN
Expression Region 1-586
Protein Description Full length protein
Storage Buffer Tris-based buffer,50% glycerol
Still Have Questions? Leave a Message or Start an on-line Chat

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