Recombinant Mouse Cerberus (Cer1)

Code CSB-YP005254MO
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Source Yeast
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Code CSB-EP005254MO
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Source E.coli
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Code CSB-EP005254MO-B
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Source E.coli
Conjugate Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code CSB-BP005254MO
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Source Baculovirus
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Code CSB-MP005254MO
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Source Mammalian cell
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Product Details

Purity
>85% (SDS-PAGE)
Target Names
Cer1
Uniprot No.
Alternative Names
Cer1; Cerl; Cerr1Cerberus; Cerberus-like protein; Cer-l; Cerberus-related protein
Species
Mus musculus (Mouse)
Expression Region
18-272
Target Protein Sequence
DLC VDGCQSQGSL SFPLLERGRR DLHVANHEEA EDKPDLFVAV PHLMGTSLAG EGQRQRGKML SRLGRFWKKP ETEFYPPRDV ESDHVSSGMQ AVTQPADGRK VERSPLQEEA KRFWHRFMFR KGPAFQGVIL PIKSHEVHWE TCRTVPFNQT IAHEDCQKVV VQNNLCFGKC SSIRFPGEGA DAHSFCSHCS PTKFTTVHLM LNCTSPTPVV KMVMQVEECQ CMVKTERGEE RLLLAGSQGS FIPGLPASKT NP
Protein Length
Full Length of Mature Protein
Tag Info
Tag type will be determined during the manufacturing process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form
Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization
Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet
Please contact us to get it.

Customer Reviews and Q&A

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Target Background

Function
Cytokine that may play a role in anterior neural induction and somite formation during embryogenesis in part, through a BMP-inhibitory mechanism. Can regulate Nodal signaling during gastrulation as well as the formation and patterning of the primitive streak.
Gene References into Functions
  1. Hhex and Cer1 are indispensable components of the Sox17 pathway for cardiopoiesis. PMID: 24585688
  2. regulates the Nodal/Bone Morphogenetic Protein antagonist Cerberus and the Baf60c/Smarcd3 subunit of the Brg1/Brm-associated factors (BAF) chromatin-remodelling complex PMID: 23787002
  3. a good marker for quantification of definitive endoderm differentiation of mouse and human ES/iPS cells PMID: 23717584
  4. Role of Cerberus-like in mouse embryogenesis PMID: 11934155
  5. Cerberus-like and Lefty-1 function redundantly to modulate Nodal signaling during gastrulation and regulate patterning of the primitive streak PMID: 12431380
  6. Some early Cer1-expressing cells do contribute to the AVE when it becomes established at E5.5. PMID: 17662710
  7. successful identification of an association with CER1 in humans together with our mouse study suggests that CER1 may play a role in the development of bone or its metabolism PMID: 19113921

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Subcellular Location
Secreted.
Protein Families
DAN family
Database Links
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