Recombinant Mouse Dopamine beta-hydroxylase (Dbh), partial

Code CSB-YP714478MO
MSDS
Size Pls inquire
Source Yeast
Have Questions? Leave a Message or Start an on-line Chat
Code CSB-EP714478MO
MSDS
Size Pls inquire
Source E.coli
Have Questions? Leave a Message or Start an on-line Chat
Code CSB-EP714478MO-B
MSDS
Size Pls inquire
Source E.coli
Conjugate Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
Have Questions? Leave a Message or Start an on-line Chat
Code CSB-BP714478MO
MSDS
Size Pls inquire
Source Baculovirus
Have Questions? Leave a Message or Start an on-line Chat
Code CSB-MP714478MO
MSDS
Size Pls inquire
Source Mammalian cell
Have Questions? Leave a Message or Start an on-line Chat

Product Details

Purity
>85% (SDS-PAGE)
Target Names
Dbh
Uniprot No.
Alternative Names
DbhDopamine beta-hydroxylase; EC 1.14.17.1; Dopamine beta-monooxygenase) [Cleaved into: Soluble dopamine beta-hydroxylase]
Species
Mus musculus (Mouse)
Protein Length
Partial
Tag Info
Tag type will be determined during the manufacturing process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form
Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization
Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet
Please contact us to get it.

Customer Reviews and Q&A

 Customer Reviews

There are currently no reviews for this product.

Submit a Review here

Target Background

Function
Conversion of dopamine to noradrenaline.
Gene References into Functions
  1. In mice, hepatic Dbh mRNA levels correlated with cardiovascular risk phenotypes. PMID: 25326128
  2. Dbh-deficient mice exhibit shorter latencies to loss of righting reflex and longer durations of hypersensitivity to general anesthesia. PMID: 23042227
  3. our results suggest that DBH knockout mice have normal levels of dopamine 2 receptors in the high-affinity state and that additional mechanisms contribute to their behavioral sensitivity to psychostimulants PMID: 20336622
  4. These results strongly suggest that the norepinephrine defect in Mecp2(-/Y) mice is likely to result from deficient expression of not only tyrosine hydroxylase but also DBH without significant loss of catecholaminergic neurons in the locus coeruleus. PMID: 20193660
  5. Dbh-/- animals were hypersensitive to the behavioral effects of amphetamine. PMID: 12370425
  6. A mutation in the ATP7B copper transporter causes reduced levels of this enzyme and norepinephrine in the mouse adrenal gland. PMID: 12718440
  7. The response of mice deficient in this gene to cholecystokinin-8 induced satiety PMID: 12736175

Show More

Hide All

Subcellular Location
[Soluble dopamine beta-hydroxylase]: Cytoplasmic vesicle, secretory vesicle lumen. Cytoplasmic vesicle, secretory vesicle, chromaffin granule lumen.; Cytoplasmic vesicle, secretory vesicle membrane; Single-pass type II membrane protein. Cytoplasmic vesicle, secretory vesicle, chromaffin granule membrane; Single-pass type II membrane protein.
Protein Families
Copper type II ascorbate-dependent monooxygenase family
Tissue Specificity
Detected in adrenal gland secretory granules (at protein level). Detected in adrenal gland.
Database Links
icon of phone
Call us
301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
icon of address
Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
icon of social media
Join us with

Subscribe newsletter

Leave a message

* To protect against spam, please pass the CAPTCHA test below.
CAPTCHA verification
© 2007-2024 CUSABIO TECHNOLOGY LLC All rights reserved. 鄂ICP备15011166号-1