Recombinant Mouse Forkhead box protein I1 (Foxi1)

Code CSB-YP849730MO
MSDS
Size Pls inquire
Source Yeast
Have Questions? Leave a Message or Start an on-line Chat
Code CSB-EP849730MO
MSDS
Size Pls inquire
Source E.coli
Have Questions? Leave a Message or Start an on-line Chat
Code CSB-EP849730MO-B
MSDS
Size Pls inquire
Source E.coli
Conjugate Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
Have Questions? Leave a Message or Start an on-line Chat
Code CSB-BP849730MO
MSDS
Size Pls inquire
Source Baculovirus
Have Questions? Leave a Message or Start an on-line Chat
Code CSB-MP849730MO
MSDS
Size Pls inquire
Source Mammalian cell
Have Questions? Leave a Message or Start an on-line Chat

Product Details

Purity
>85% (SDS-PAGE)
Target Names
Foxi1
Uniprot No.
Alternative Names
Foxi1Forkhead box protein I1
Species
Mus musculus (Mouse)
Expression Region
1-372
Target Protein Sequence
MSSFDLPAPS PPRCSPQFPS IGQEPPEMNL YYENFFHPQG MPSPQRPTSF EGGGEYGTTP NPYLWLNGPA MTPPPYLPGT NASPFLPQAY GMQRQLLPSD LGWLPIPSQE ELMKLVRPPY SYSALIAMAI HGAPDQRLTL SQIYQYVADN FPFYNKSKAG WQNSIRHNLS LNDCFKKVPR DEDDPGKGNY WTLDPNCEKM FDNGNFRRKR KRKSDSSSST SSLASEKTEN GLLASSPKPT EPQEVLDTAS PDTTTSSPEK RSSPAPSGTP CLNNFLSTMT AYVSGTNPIS RSVATPGLSS EPIDKMGQNS LNFNSYTPLT NLSSHGNGGE WANPVATNAL GYGGSVFNQF SPHFYNSINT NGILFPREGT EV
Protein Length
full length protein
Tag Info
Tag type will be determined during the manufacturing process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form
Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization
Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet
Please contact us to get it.

Customer Reviews and Q&A

 Customer Reviews

There are currently no reviews for this product.

Submit a Review here

Target Background

Function
Transcriptional activator required for the development of normal hearing, sense of balance and kidney function. Required for the expression of SLC26A4/PDS, JAG1 and COCH in a subset of epithelial cells and the development of the endolymphatic system in the inner ear. Also required for the expression of SLC4A1/AE1, SLC4A9/AE4, ATP6V1B1 and the differentiation of intercalated cells in the epithelium of distal renal tubules.
Gene References into Functions
  1. mutations in FOXI1 could prove to cause a Pendred syndrome-like human deafness PMID: 12642503
  2. examined the expression patterns of the Foxi class genes from embryonic day 6.5 to 10.5; Foxi1 expression is first detected in the endolymphatic duct in the otic vesicle at E10.5 PMID: 15376323
  3. The AE4 promoter is identified as a direct target of Foxi1. PMID: 16159312
  4. Spermatozoa from Foxi1 null males fail to reach the female genital tract in sufficient number to allow fertilization. PMID: 16932748
  5. Data suggestthat Foxi1 is necessary for expression of at least four subunits in three different epithelia and most likely is a major determinant for proper assembly of a functional vacuolar H(+)-ATPase complex at these locations. PMID: 19214237
  6. Foxa1 and Foxi1 are required for later stage sweat gland development. PMID: 19270025

Show More

Hide All

Subcellular Location
Nucleus.
Tissue Specificity
Expressed in intercalated cells of the epithelium of the distal renal tubule.
Database Links
icon of phone
Call us
301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
icon of address
Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
icon of social media
Join us with

Subscribe newsletter

Leave a message

* To protect against spam, please pass the CAPTCHA test below.
CAPTCHA verification
© 2007-2024 CUSABIO TECHNOLOGY LLC All rights reserved. 鄂ICP备15011166号-1