GTP-binding protein Rit2
Ras-like protein expressed in neurons
Ras-like without CAAX protein 2
Store at -20°C, for extended storage, conserve at -20°C or -80°C.
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Binds and exchanges GTP and GDP. Binds and modulates the activation of POU4F1 as gene expression regulator.
Nucleus, Cell membrane
Small GTPase superfamily, Ras family
Expressed in ganglion cell layer (GCL), inner plexiform layer (IPL) and inner nuclear layer (INL) of the retina. Expressed in retinal ganglion cells (RGCs). Expressed in horizontal, bipolar and amacrine cells, but not Mueller glia, of the INL (at protein